Evidence map›Paper›PMID 30670535›Full record

ArticleBlood advances2019

Baseline and interim functional imaging with PET effectively risk stratifies patients with peripheral T-cell lymphoma.

Neha Mehta-Shah, Kimiteru Ito, Kurt Bantilan, Alison J Moskowitz, Craig Sauter, Steven M Horwitz, Heiko Schöder

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Neha Mehta-ShahLymphoma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0001-5744-0670
Kimiteru ItoMolecular Imaging and Therapy Service, Department of Radiology, and.
Kurt BantilanLymphoma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Alison J MoskowitzLymphoma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Craig SauterBone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Steven M HorwitzLymphoma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0002-6399-2006
Heiko SchöderMolecular Imaging and Therapy Service, Department of Radiology, and.
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Washington University Paul Calabresi K12 Career Development Award for Clinical OncologyK12CA167540 · NCI · WASHINGTON UNIVERSITY · PI John F. Dipersio, Ramaswamy Govindan · 2012 to 2026
$11.7M
NCI NIH HHS K12 CA167540NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

The prognosis of peripheral T-cell lymphoma (PTCL) is heterogenous. Baseline or interim imaging characteristics may inform risk-adapted treatment paradigms. We identified 112 patients with PTCL who were consecutively treated with cyclophosphamide, doxorubicin, vincristine, prednisone (CHOP)/CHOP-like regimens with the intent to consolidate with an autologous transplant. Baseline (n = 93) and interim (after 4 cycles, n = 99) positron emission tomography (PET) images were reevaluated, and we calculated baseline total metabolic tumor volume (TMTV). Interim PET (iPET) responses were graded visually by 5-point score (i5PS) and by percentage change of standardized uptake value. By univariate analysis, predictors of event-free survival (EFS) included Prognostic Index for Peripheral TCL (PIT) higher than 1 (hazard ratio [HR], 1.83;

Indexed as

Positron-Emission TomographyAdultAgedAntineoplastic Combined Chemotherapy ProtocolsCyclophosphamideDoxorubicinFemaleFluorodeoxyglucose F18HumansLymphoma, T-Cell, PeripheralMaleMiddle AgedMultimodal ImagingNeoplasm MetastasisNeoplasm StagingPositron Emission Tomography Computed TomographyCyclophosphamideDoxorubicinFluorodeoxyglucose F18PrednisoneVincristine

Identifiers

PMID30670535
PMCPMC6341183
OpenAlexW2911364860

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.