ArticleLipids in health and disease2019
The triglyceride paradox in the mortality of coronary artery disease.
Article in Lipids in health and disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Association Between Total Cholesterol and In-Hospital Mortality Among First-Episode Acute Coronary Syndrome Patients: Multilevel Analysis from NCVD-ACS Registry.Healthcare (Basel, Switzerland) · 2026Article
- Triglyceride levels and all-cause mortality in patients with left main coronary artery disease undergoing percutaneous coronary intervention.Frontiers in cardiovascular medicine · 2026Article
- A comprehensive study on the uric acid to high-density cholesterol ratio influencing cardiometabolic-based chronic disease in China.Frontiers in nutrition · 2026Article
- Triglycerides, Glucose Metabolism, and Type 2 Diabetes.International journal of molecular sciences · 2025Review
- Metabolic syndrome and the risk of incident heart failure: a prospective cohort study.American journal of preventive cardiology · 2025Article
- Prognostic value of triglyceride-glucose index in patients with cardiovascular-kidney-metabolic syndrome undergoing percutaneous coronary intervention.Frontiers in cardiovascular medicine · 2025Article
- Association between cardiometabolic index and all-cause and cause-specific mortality among the general population: NHANES 1999-2018.Lipids in health and disease · 2024Article
- Association between atherogenic index of plasma and all-cause mortality and specific-mortality: a nationwide population‑based cohort study.Cardiovascular diabetology · 2024Article
- Article
- Association between metabolic score for insulin resistance and clinical outcomes: insights from the Tehran lipid and glucose study.Nutrition & metabolism · 2024Article
- The impact of triglyceride glucose-body mass index on all-cause and cardiovascular mortality in elderly patients with diabetes mellitus: evidence from NHANES 2007-2016.BMC geriatrics · 2024Article
- Correlations Between Acute Coronary Syndrome and Novel Inflammatory Markers (Systemic Immune-Inflammation Index, Systemic Inflammation Response Index, and Aggregate Index of Systemic Inflammation) in Patients with and without Diabetes or Prediabetes.Journal of inflammation research · 2024Article
- The triglyceride glucose index was U-shape associated with all-cause mortality in population with cardiovascular diseases.Diabetology & metabolic syndrome · 2023Article
- The Ketogenic Diet and Cardiovascular Diseases.Nutrients · 2023Review
- Article
- Comparison of the effects of triglyceride variability and exposure estimate on clinical prognosis in diabetic patients.Cardiovascular diabetology · 2022Article
- Relationship Between Non-fasting Triglycerides and Cardiovascular Disease Mortality in a 20-year Follow-up Study of a Japanese General Population: NIPPON DATA90.Journal of epidemiology · 2022Article
- Self- vs provider-referral differences for coronary artery calcium testing.American heart journal plus : cardiology research and practice · 2022Article
- Omega-3 Fatty Acids and Coronary Artery Disease: More Questions Than Answers.Journal of clinical medicine · 2021Review
- The Associations of Lipid Profiles With Cardiovascular Diseases and Death in a 10-Year Prospective Cohort Study.Frontiers in cardiovascular medicine · 2021Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
backgroundThe role of triglyceride (TG) in secondary prevention of patients with coronary artery disease (CAD) was debated. In the present study, we assessed the association between admission TG levels and long-term mortality risk in CAD patients.
methodsA retrospective analysis was conducted from a single registered database. 3061 consecutive patients with CAD confirmed by coronary angiography were enrolled and were grouped into 3 categories by the tertiles of admission serum TG levels. The primary end point in this study was all-cause mortality and the secondary end point was cardiovascular mortality.
resultsThe mean follow-up time was 26.9 ± 13.6 months and death events occurred in 258 cases and cardiovascular death events occurred in 146 cases. Cumulative survival curves indicated that the risk of all-cause death decreased with increasing TG level (Tertile 1 vs. Tertile 2 vs. Tertile 3 = 10.3% vs. 8.6% vs. 6.3%, log rank test for overall p = 0.001). Cox regression analysis showed an independent correlation between TG level and risk of all-cause mortality [hazard ratio (HR) 0.71, 95% confidence interval (CI) 0.58-0.86] and cardiovascular mortality (HR 0.67, 95% CI 0.51-0.89) in total patients with CAD. Subgroup analysis found the similar results in patients with acute coronary syndrome and acute myocardial infarction.
conclusionsThis study found an inverse association between TG levels and mortality risk in CAD patients, which suggests that the "TG paradox" may exist in CAD patients.
trial registrationChiCTR, ChiCTR-OOC-17010433 . Registered 17 February 2017 - Retrospectively registered.
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