Evidence map›Paper›PMID 30670040›Full record

SynthesisHealth and quality of life outcomes2019

Quality of life in bladder cancer patients receiving medical oncological treatment; a systematic review of the literature.

G A Taarnhøj, C Johansen, H Pappot

Erratum issuedOpen access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Health and quality of life outcomes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Health-related quality of life overview after different curative treatment options in muscle-invasive bladder cancer: an umbrella review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Pooled it
  4. Trial
  5. Trial
  6. Bridging gaps in care: medical student home visits and their influence on radiation oncology patients.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Searching for a harmonious survival: the experience of quality of life of urological cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Observational
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

G A TaarnhøjDepartment of Oncology, Rigshospitalet, Blegdamsvej 9, section 5073, 2100, Copenhagen Ø, Denmark.
C JohansenDepartment of Oncology, Rigshospitalet, Blegdamsvej 9, section 5073, 2100, Copenhagen Ø, Denmark.
H PappotDepartment of Oncology, Rigshospitalet, Blegdamsvej 9, section 5073, 2100, Copenhagen Ø, Denmark. helle.pappot@regionh.dk.ORCID http://orcid.org/0000-0002-3570-5372
Rigshospitalet · DK

Funding

Kræftens Bekæmpelse R150-A10114
6 · The paper itself

Abstract

backgroundPrevious quality of life (QoL) literature in bladder cancer (BC) patients has focused on finding the preferred urinary diversion while little is known about the QoL of patients in medical oncological treatment (MOT). We performed a systematic review to assess the existing literature on QoL in patients with muscle-invasive BC (MIBC) undergoing MOT.

methodsA systematic search of Pubmed and Embase was performed. Inclusion criteria were studies containing QoL data for patients undergoing chemo- and/or radiotherapy. We extracted all QoL scorings at different time intervals and on the six most prevalent domains: overall QoL, urinary, bowel sexual symptoms, pain and fatigue. The study was carried out according to PRISMA guidelines for systematic reviews and GRADE was used to rate the quality of evidence from the included studies.

resultsOf 208 papers reviewed, 21 papers were included. Twenty-one different QoL instruments were applied. The only data on QoL during chemotherapy was from patients in clinical trials investigating new treatments. No studies were found for patients in neoadjuvant treatment. The level of evidence at each time point was graded as very low to moderate. From the studies included the overall QoL seemed inversely related to the organ-specific impairment from sexual and urinary symptoms and increased with decreasing organ-specific symptoms for long term survivors > 6 months after treatment.

conclusionsCollection of data on QoL from patients with MIBC disease undergoing MOT has been sparse and diverse. The present data can act as a summary but prompts for more prospective collection of QoL data from BC patients.

Indexed as

Quality of LifeFemaleHumansMaleProspective StudiesUrinary Bladder NeoplasmsBladder cancerChemotherapyMuscle-invasive bladder cancerQuality of lifeUrothelial cancer

Identifiers

PMID30670040
PMCPMC6341712
OpenAlexW2912440854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.