Evidence map›Paper›PMID 30669652›Full record

ArticleViruses2019

Design and Preclinical Development of a Phage Product for the Treatment of Antibiotic-Resistant

Susan M Lehman, Gillian Mearns, Deborah Rankin, Robert A Cole, Frenk Smrekar, Steven D Branston, Sandra Morales

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed
20.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 150 citations in OpenAlex.

  1. Trial
  2. Engineering the probioticSynthetic and systems biotechnology · 2026
    Article
  3. Review
  4. mBio · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
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  17. Article
  18. Review
  19. Article
  20. Article

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Susan M LehmanAmpliPhi Biosciences, San Diego, CA 92130, USA. sml@ampliphibio.com.
Gillian MearnsAmpliPhi Australia, Sydney, NSW 2100, Australia. gm@ampliphibio.com.
Deborah RankinAmpliPhi Australia, Sydney, NSW 2100, Australia. dar@ampliphibio.com.
Robert A ColeAmpliPhi Australia, Sydney, NSW 2100, Australia. rac@ampliphibio.com.
Frenk SmrekarAmpliPhi d.o.o., 1261 Ljubljana-Dobrunje, Slovenia. frenk.smrekar@jafral.com.
Steven D BranstonAmpliPhi Australia, Sydney, NSW 2100, Australia. sb@ampliphibio.com.
Sandra MoralesAmpliPhi Australia, Sydney, NSW 2100, Australia. spm@ampliphibio.com.ORCID 0000-0001-7085-2864
AmpliPhi Biosciences (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteriophages, viruses that only kill specific bacteria, are receiving substantial attention as nontraditional antibacterial agents that may help alleviate the growing antibiotic resistance problem in medicine. We describe the design and preclinical development of AB-SA01, a fixed-composition bacteriophage product intended to treat

Indexed as

Phage TherapyAnimalsFemaleGenome, ViralMethicillin-Resistant Staphylococcus aureusMiceMyoviridaeStaphylococcal InfectionsStaphylococcus Phagesantimicrobialbacteriophagebiofilmfrequency of resistancenontraditional antibacterialphage sensitivityphage therapyresistance managementStaphylococcus aureus

Identifiers

PMID30669652
PMCPMC6356596
OpenAlexW2910071029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.