ReviewInternational journal of molecular sciences2019
Bactericidal and Cytotoxic Properties of Silver Nanoparticles.
Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 347 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
347 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Green-Synthesized Silver Nanoparticles Against Acinetobacter baumannii: A Systematic Review of Antibacterial Activity, Mechanisms of Action, Toxicity, and Antibiofilm Effects.MicrobiologyOpen · 2026Pooled it
- The Application of Silver to Decontaminate Dental Unit Waterlines-a Systematic Review.Biological trace element research · 2022Pooled it
- Targeting Oxidative and Immune Dysregulation in Wound Healing via Gold Nanoparticle Conjugate Chitosan.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Extracellular and Intracellular Bacterial Compounds in the Synthesis of Inorganic Particles: Silver Nanoparticles.International journal of molecular sciences · 2026Article
- Immuno-engineered conductive hydrogels: Bridging neural signaling and microenvironmental remodeling for neural repair.Materials today. Bio · 2026Article
- Biosynthesis of Silver Nanoparticles fromBiology · 2026Article
- Silver Nanoparticle-Functionalized Medical Devices for Primary Prevention of Healthcare-Associated Infections: In Vitro Efficacy Against Multidrug-Resistant Clinical Isolates.Microorganisms · 2026Article
- Degradation-tunable coating with sustained silver release for spinal implants to prevent postoperative infections.Bioactive materials · 2026Article
- Nanotechnology-mediated strategies for skeletal muscle repair and regeneration: targeted intervention, functional remodeling, and translational challenges.Journal of nanobiotechnology · 2026Review
- Green-Synthesized vs. Chemical Silver Nanoparticles: A Comparative Study onMicroorganisms · 2026Article
- Potential of Silver Nanoparticles in Imaging Diagnostics and Image-Guided Applications: A Narrative Review.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Comparative Cytocompatibility and Oxidative Stress Analysis of Green-Synthesized Nano-Silver Fluoride and Silver Diamine Fluoride in Human Gingival Fibroblasts.Journal of functional biomaterials · 2026Article
- MIC and MBC of silver nanoparticles in antibiotic-resistantOpen veterinary journal · 2026Article
- Review
- Contact-Dependent Antibacterial Performance of Silver Nanoparticles Encapsulated in Collagen-Based Gels.Journal of functional biomaterials · 2026Article
- Matrix-Dependent Stability and Antibacterial Efficacy of Silver Nanoparticles: A Comparative Study of Anionic Carbopol vs. Non-Ionic Pluronic Hydrogels.Pharmaceutics · 2026Article
- Green synthesis of silver nanoparticles using Rumex. crispus seeds and synergistic application of photodynamic/photothermal antimicrobial therapy.BMC biotechnology · 2026Article
- Nanomaterials as electrochemical regulators of bacterial biofilms through the modulation of extracellular electron transport and ion channels.Journal of nanobiotechnology · 2026Review
- Article
- Emergence of multidrug-resistant Staphylococcus epidermidis in Nile tilapia (Oreochromis spp.): virulence, antimicrobial resistance, and nanoparticle-based control.BMC veterinary research · 2026Article
287 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Silver nanoparticles (AgNPs) can be synthesized from a variety of techniques including physical, chemical and biological routes. They have been widely used as nanomaterials for manufacturing cosmetic and healthcare products, antimicrobial textiles, wound dressings, antitumor drug carriers, etc. due to their excellent antimicrobial properties. Accordingly, AgNPs have gained access into our daily life, and the inevitable human exposure to these nanoparticles has raised concerns about their potential hazards to the environment, health, and safety in recent years. From in vitro cell cultivation tests, AgNPs have been reported to be toxic to several human cell lines including human bronchial epithelial cells, human umbilical vein endothelial cells, red blood cells, human peripheral blood mononuclear cells, immortal human keratinocytes, liver cells, etc. AgNPs induce a dose-, size- and time-dependent cytotoxicity, particularly for those with sizes ≤10 nm. Furthermore, AgNPs can cross the brain blood barrier of mice through the circulation system on the basis of in vivo animal tests. AgNPs tend to accumulate in mice organs such as liver, spleen, kidney and brain following intravenous, intraperitoneal, and intratracheal routes of administration. In this respect, AgNPs are considered a double-edged sword that can eliminate microorganisms but induce cytotoxicity in mammalian cells. This article provides a state-of-the-art review on the synthesis of AgNPs, and their applications in antimicrobial textile fabrics, food packaging films, and wound dressings. Particular attention is paid to the bactericidal activity and cytotoxic effect in mammalian cells.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.