Evidence map›Paper›PMID 30669601›Full record

ArticleViruses2019

Aerosol and Contact Transmission Following Intranasal Infection of Mice with Japanese Encephalitis Virus.

Chunxia Chai, Rachel Palinski, Yixuan Xu, Qiao Wang, Sanjie Cao, Yi Geng, Qin Zhao, Yiping Wen, Xiaobo Huang, Qiguai Yan and 6 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Airborne transmission of common swine viruses.Porcine health management · 2023
    Review
  7. Review
  8. Aerosolized Zika virus infection in Guinea pigs.Emerging microbes & infections · 2022
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Chunxia ChaiResearch Center of Swine Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. chaichunxia_ccx@126.com.
Rachel PalinskiDepartment of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA. rpalinski@vet.k-state.edu.
Yixuan XuResearch Center of Swine Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. xyxtk@foxmail.com.
Qiao WangResearch Center of Swine Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. wangqiao666666@126.com.
Sanjie CaoResearch Center of Swine Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. csanjie@sicau.edu.cn.
Yi GengCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. gengyisicau@126.com.
Qin ZhaoResearch Center of Swine Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. zhaoqinde@foxmail.com.
Yiping WenResearch Center of Swine Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. yueliang5189@163.com.
Xiaobo HuangResearch Center of Swine Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. rsghb110@126.com.
Qiguai YanResearch Center of Swine Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. yanqigui@126.com.
Xiaoping MaResearch Center of Swine Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. mxp886@sina.com.cn.
Xintian WenResearch Center of Swine Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. Xintian3211@126.com.
Yong HuangResearch Center of Swine Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. hyong601@163.com.
Xinfeng HanResearch Center of Swine Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. hanxinf@163.com.
Wenjun MaDepartment of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA. wma@vet.k-state.edu.
Rui WuResearch Center of Swine Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. wurui1977@sicau.edu.cn.ORCID 0000-0001-7791-4167
Sichuan Agricultural University · CNKansas State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Japanese encephalitis virus (JEV), a causative agent of severe viral encephalitis in humans, has a biological cycle fluctuating between transmission in mosquitoes and avian species and amplification in pigs. Contact transmission of JEV was recently shown in pigs in the absence of arthropod vectors. Here, we show JEV transmission between infected and contact mice and further demonstrate that JEV transmission occurs between animals via aerosols, as both viral RNA and infectious JEV were detected in direct contact- and aerosol-exposed contact animals. The results of this study change our understanding of JEV transmission in densely populated regions and may help to explain JEV outbreaks without the presence of arthropod vectors.

Indexed as

AerosolsViral TropismAnimalsEncephalitis, JapaneseEncephalitis Virus, JapaneseFemaleGenotypeMiceMice, Inbred BALB CNasal AbsorptionRNA, ViralSpecific Pathogen-Free OrganismsVirus SheddingAerosolsRNA, Viralaerosol transmissioncontact transmissionintranasal infectionJEVmice

Identifiers

PMID30669601
PMCPMC6356382
OpenAlexW2910090195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.