Evidence map›Paper›PMID 30669523›Full record

ReviewMaterials (Basel, Switzerland)2019

A Precautionary Approach to Guide the Use of Transition Metal-Based Nanotechnology to Prevent Orthopedic Infections.

Marta Bottagisio, Arianna B Lovati, Fabio Galbusera, Lorenzo Drago, Giuseppe Banfi

Abstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Journal of functional biomaterials · 2023
    Article
  2. Article
  3. Article
  4. Article
  5. Controlled phage therapy by photothermal ablation of specific bacterial species using gold nanorods targeted by chimeric phages.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marta BottagisioIRCCS Orthopedic Institute Galeazzi, Laboratory of Clinical Chemistry and Microbiology, Via R. Galeazzi 4, 20161 Milan, Italy. marta.bottagisio@grupposandonato.it.ORCID 0000-0001-8105-5959
Arianna B LovatiIRCCS Orthopedic Institute Galeazzi, Cell and Tissue Engineering Laboratory, Via R. Galeazzi 4, 20161 Milan, Italy. arianna.lovati@grupposandonato.it.
Fabio GalbuseraIRCCS Orthopedic Institute Galeazzi, Laboratory of Biological Structures Mechanics, Via R. Galeazzi 4, 20161 Milan, Italy. fabio.galbusera@grupposandonato.it.
Lorenzo DragoLaboratory of Clinical Microbiology, Department of Biomedical Sciences for Health, University of Milan, 20133 Milan, Italy. lorenzo.drago@unimi.it.ORCID 0000-0002-5206-540X
Giuseppe BanfiIRCCS Orthopedic Institute Galeazzi, Laboratory of Experimental Biochemistry & Molecular Biology, Via R. Galeazzi 4, 20161 Milan, Italy. banfi.giuseppe@fondazionesanraffaele.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increase of multidrug-resistant bacteria remains a global concern. Among the proposed strategies, the use of nanoparticles (NPs) alone or associated with orthopedic implants represents a promising solution. NPs are well-known for their antimicrobial effects, induced by their size, shape, charge, concentration and reactive oxygen species (ROS) generation. However, this non-specific cytotoxic potential is a powerful weapon effective against almost all microorganisms, but also against eukaryotic cells, raising concerns related to their safe use. Among the analyzed transition metals, silver is the most investigated element due to its antimicrobial properties

Indexed as

antibacterial coatingsantibiotic-resistant microorganismsbiofilmnanoparticlesorthopedic infectionstransition metals

Identifiers

PMID30669523
PMCPMC6356474

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.