Evidence map›Paper›PMID 30669515›Full record

ArticleToxins2019

Simultaneous Lateral Flow Immunoassay for Multi-Class Chemical Contaminants in Maize and Peanut with One-Stop Sample Preparation.

Du Wang, Jianguo Zhu, Zhaowei Zhang, Qi Zhang, Wen Zhang, Li Yu, Jun Jiang, Xiaomei Chen, Xuefang Wang, Peiwu Li

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 46 citations in OpenAlex.

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  11. An Open Sandwich Immunochromatography for Non-competitive Detection of Small Antigens.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2021
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Du WangOil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan 430062, China. wangdu@caas.cn.
Jianguo ZhuOil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan 430062, China. jianguozhu01@126.com.
Zhaowei ZhangOil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan 430062, China. zwzhang@whu.edu.cn.ORCID 0000-0002-6686-2995
Qi ZhangOil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan 430062, China. zhangqi01@caas.cn.
Wen ZhangOil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan 430062, China. zhangwen@oilcrops.cn.
Li YuOil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan 430062, China. yuli01@caas.cn.
Jun JiangOil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan 430062, China. jiangjun@caas.cn.
Xiaomei ChenOil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan 430062, China. chenxiaomei@caas.cn.
Xuefang WangOil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan 430062, China. wangxuefang01@caas.cn.
Peiwu LiOil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan 430062, China. peiwuli@oilcrops.cn.
Chinese Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multi-class chemical contaminants, such as pesticides and mycotoxins, are recognized as the major risk factors in agro products. It is thus necessary to develop rapid and simple sensing methods to fulfill the on-site monitoring of multi-class chemical contaminants with different physicochemical properties. Herein, a lateral flow immunoassay via time-resolved fluorescence was developed for the rapid, on-site, simultaneous, and quantitative sensing aflatoxin B₁ (AFB₁), zearalenone (ZEA), and chlorothalonil (CTN) in maize and peanut. The sample preparation was optimized to a single step, combining the grinding and extraction. Under optimal conditions, the sensing method lowered the limits of detection (LOD) to 0.16, 0.52, and 1.21 µg/kg in maize and 0.18, 0.57, and 1.47 µg/kg in peanut with an analytical range of 0.48⁻20, 1.56⁻200, and 3.63⁻300 µg/kg for AFB₁, ZEA and CTN, respectively. The protocol could be completed within 15 min, including sample preparation and lateral flow immunoassay. The recovery range was 83.24⁻110.80%. An excellent correlation was observed between this approach and high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) for mycotoxins and gas chromatography-tandem mass spectrometry (GC-MS/MS) for pesticide in maize and peanut. This work could be applied in on-site multi-class sensing for food safety.

Indexed as

Aflatoxin B1ArachisChromatography, High Pressure LiquidFood ContaminationFungicides, IndustrialGas Chromatography-Mass SpectrometryImmunoassayNitrilesTandem Mass SpectrometryZea maysZearalenoneAflatoxin B1Fungicides, IndustrialNitrilestetrachloroisophthalonitrileZearalenoneaflatoxin B1chlorothalonilmaize and peanutmulti-class chemical contaminantssimultaneous lateral flow immunoassayzearalenone

Identifiers

PMID30669515
PMCPMC6356774
OpenAlexW2911976519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.