Evidence map›Paper›PMID 30669495›Full record

ArticleInternational journal of molecular sciences2019

Effect of Polymer Phase Transition Behavior on Temperature-Responsive Polymer-Modified Liposomes for siRNA Transfection.

Kenichi Nagase, Momoko Hasegawa, Eri Ayano, Yoshie Maitani, Hideko Kanazawa

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Polymerization from Lipid Membranes.Biomacromolecules · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Temperature-modulated separation of therapeutic cells, viral vectors, and exosomes using functional polymers.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Bioanalytical technologies using temperature-responsive polymers.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2024
    Review
  14. Stimuli-Responsive Nanotechnology for RNA Delivery.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kenichi NagaseFaculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato, Tokyo 105-8512, Japan. nagase-kn@pha.keio.ac.jp.
Momoko HasegawaFaculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato, Tokyo 105-8512, Japan. peach-hasegawa.3720048@z6.keio.jp.
Eri AyanoFaculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato, Tokyo 105-8512, Japan. ayano-er@pha.keio.ac.jp.
Yoshie MaitaniFaculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato, Tokyo 105-8512, Japan. maitani-y@u01.gate01.com.
Hideko KanazawaFaculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato, Tokyo 105-8512, Japan. kanazawa-hd@pha.keio.ac.jp.

Funding

Ministry of Education, Culture, Sports, Science and Technology S1411004
6 · The paper itself

Abstract

Small interfering RNAs (siRNAs) have been attracting significant attention owing to their gene silencing properties, which can be utilized to treat intractable diseases. In this study, two temperature-responsive liposomal siRNA carriers were prepared by modifying liposomes with different polymers-poly(

Indexed as

LiposomesPhase TransitionTemperatureTransfectionCell LineCell SurvivalGene ExpressionGene SilencingGenes, ReporterHumansMagnetic Resonance SpectroscopyMolecular StructureMolecular WeightPolymersRNA InterferenceRNA, Small InterferingLiposomesPolymersRNA, Small InterferingliposomesiRNA deliverythermoresponsive polymertransfection

Identifiers

PMID30669495
PMCPMC6358841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.