ReviewInternational journal of molecular sciences2019
Antifouling (Bio)materials for Electrochemical (Bio)sensing.
Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 157 citations in OpenAlex.
- Design and Simulation of Lamotrigine Intermittent Release from a Subcutaneous Implant with an Enzymatic Biosensor Based on Clinical Data.Biosensors · 2026Article
- Why Sensors Fail in Biological Samples: Fouling, Blocking, Matrix Effects and Prevention Solutions.International journal of molecular sciences · 2026Review
- Molecularly Imprinted Polymer (MIP)-Based Electrochemical Sensors for Pharmaceutical Detection in Wastewater: Imprinting Strategies, Analytical Performance, and Challenges.Sensors (Basel, Switzerland) · 2026Review
- Electrochemical liquid biopsy across cancer care pathway.The journal of liquid biopsy · 2026Review
- Advanced biosensing strategies for high-risk foodborne pathogens: a comprehensive review ofFood chemistry. Molecular sciences · 2026Review
- Review
- Comparing UV-enhanced and direct reduction strategies for CD8⁺ T-cell electrochemical detection.Scientific reports · 2026Article
- Non-Invasive Electrochemical Biosensors for Fibromyalgia: A Path Toward Objective Physiological Monitoring and Personalized Management.Sensors (Basel, Switzerland) · 2026Review
- - Invited Review - Advancing precision livestock farming: integrating artificial intelligence and emerging technologies for sustainable livestock management.Animal bioscience · 2026Article
- Point-of-Care Electrochemical Diagnostic Developments for Multidrug-Resistant Bacteria: Role of Aptamers and Nanomaterials.Biosensors · 2026Review
- Electrochemical Biosensing Platforms for Rapid and Early Diagnosis of Crop Fungal and Viral Diseases.Sensors (Basel, Switzerland) · 2026Review
- Stimuli-Responsive Nanomaterial-Based Biosensor Structures for Wound Care: pH, ROS, and Temperature Sensing Strategies.Micromachines · 2026Review
- Self-Templated Highly Porous Gold Electrodes for Antibiofouling Electrochemical (Bio)Sensors.Nanomaterials (Basel, Switzerland) · 2026Article
- Fouling Control of Ion-Selective Electrodes (ISEs) in Aquatic and Aquacultural Environments: A Comprehensive Review.Sensors (Basel, Switzerland) · 2025Review
- Biosensor-Integrated Tibial Components in Total Knee Arthroplasty: A Narrative Review of Innovations, Challenges, and Translational Frontiers.Bioengineering (Basel, Switzerland) · 2025Review
- Advanced Nanomaterial-Based Electrochemical Biosensing of Loop-Mediated Isothermal Amplification Products.Biosensors · 2025Article
- Future perspectives of GMO detection in agriculture: strategies for electrochemical nucleic acid detection.Mikrochimica acta · 2025Review
- Article
- Nanosensors and Microsensors for Body Fluid Monitoring: Various Analyte Detection and Construction Solutions.International journal of molecular sciences · 2025Review
- Recent Progress in Flexible Microelectrode Arrays for Combined Electrophysiological and Electrochemical Sensing.Biosensors · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
(Bio)fouling processes arising from nonspecific adsorption of biological materials (mainly proteins but also cells and oligonucleotides), reaction products of neurotransmitters oxidation, and precipitation/polymerization of phenolic compounds, have detrimental effects on reliable electrochemical (bio)sensing of relevant analytes and markers either directly or after prolonged incubation in rich-proteins samples or at extreme pH values. Therefore, the design of antifouling (bio)sensing interfaces capable to minimize these undesired processes is a substantial outstanding challenge in electrochemical biosensing. For this purpose, efficient antifouling strategies involving the use of carbon materials, metallic nanoparticles, catalytic redox couples, nanoporous electrodes, electrochemical activation, and (bio)materials have been proposed so far. In this article, biomaterial-based strategies involving polymers, hydrogels, peptides, and thiolated self-assembled monolayers are reviewed and critically discussed. The reported strategies have been shown to be successful to overcome (bio)fouling in a diverse range of relevant practical applications. We highlight recent examples for the reliable sensing of particularly fouling analytes and direct/continuous operation in complex biofluids or harsh environments. Opportunities, unmet challenges, and future prospects in this field are also pointed out.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.