Evidence map›Paper›PMID 30669454›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Titania Nanotubes/Hydroxyapatite Nanocomposites Produced with the Use of the Atomic Layer Deposition Technique: Estimation of Bioactivity and Nanomechanical Properties.

Aleksandra Radtke, Michalina Ehlert, Tomasz Jędrzejewski, Beata Sadowska, Marzena Więckowska-Szakiel, Jani Holopainen, Mikko Ritala, Markku Leskelä, Michał Bartmański, Marek Szkodo and 1 more

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Ultrathin ALD Coatings of Zr and V Oxides on Anodic TiOACS applied materials & interfaces · 2025
    Article
  3. Review
  4. Article
  5. TiOJournal of functional biomaterials · 2022
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aleksandra RadtkeFaculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Toruń, Poland. aradtke@umk.pl.ORCID 0000-0002-2526-0779
Michalina EhlertFaculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Toruń, Poland. m.ehlert@doktorant.umk.pl.
Tomasz JędrzejewskiFaculty of Biology and Environmental Protection, Nicolaus Copernicus University in Toruń, Lwowska 1, 87-100 Toruń, Poland. tomaszj@umk.pl.ORCID 0000-0001-8950-5643
Beata SadowskaFaculty of Biology and Environmental Protection, University of Lodz, Banacha 12/16, 90-237 Łódź, Poland. beata.sadowska@biol.uni.lodz.pl.ORCID 0000-0001-6383-3972
Marzena Więckowska-SzakielFaculty of Biology and Environmental Protection, University of Lodz, Banacha 12/16, 90-237 Łódź, Poland. marzena.wieckowska@biol.uni.lodz.pl.ORCID 0000-0003-2944-7327
Jani HolopainenDepartment of Chemistry, University of Helsinki, A.I. Virtasen aukio 1, 00014 Helsinki, Finland. jani.h.holopainen@outlook.com.
Mikko RitalaDepartment of Chemistry, University of Helsinki, A.I. Virtasen aukio 1, 00014 Helsinki, Finland. mikko.ritala@helsinki.fi.
Markku LeskeläDepartment of Chemistry, University of Helsinki, A.I. Virtasen aukio 1, 00014 Helsinki, Finland. markku.leskela@helsinki.fi.ORCID 0000-0001-5830-2800
Michał BartmańskiFaculty of Mechanical Engineering, Gdańsk University of Technology, Gabriela Narutowicza 11/12, 80-233 Gdańsk, Poland. michal.bartmanski@pg.edu.pl.ORCID 0000-0003-0185-6460
Marek SzkodoFaculty of Mechanical Engineering, Gdańsk University of Technology, Gabriela Narutowicza 11/12, 80-233 Gdańsk, Poland. marek.szkodo@pg.edu.pl.ORCID 0000-0002-4210-0718
Piotr PiszczekFaculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Toruń, Poland. piszczek@chem.umk.pl.ORCID 0000-0002-0768-8165

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Titanium dioxide nanotubes/hydroxyapatite nanocomposites were produced on a titanium alloy (Ti6Al4V/TNT/HA) and studied as a biocompatible coating for an implant surface modification. As a novel approach for this type of nanocomposite fabrication, the atomic layer deposition (ALD) method with an extremely low number of cycles was used to enrich titania nanotubes (TNT) with a very thin hydroxyapatite coating. X-ray diffraction (XRD) and scanning electron microscopy (SEM) were used for determination of the structure and the surface morphology of the fabricated nanocoatings. The biointegration activity of the layers was estimated based on fibroblasts' proliferation on the TNT/HA surface. The antibacterial activity was determined by analyzing the ability of the layers to inhibit bacterial colonization and biofilm formation. Mechanical properties of the Ti6Al4V/TNT/HA samples were estimated by measuring the hardness, Young's module, and susceptibility to scratching. The results revealed that the nanoporous titanium alloy coatings enriched with a very thin hydroxyapatite layer may be a promising way to achieve the desired balance between biofunctional and biomechanical properties of modern implants.

Indexed as

atomic layer depositionhydroxyapatitenanotubesTi6Al4Vtitania

Identifiers

PMID30669454
PMCPMC6359504

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.