Evidence map›Paper›PMID 30669387›Full record

ArticleMarine drugs2019

Protective Effect of Low Molecular Weight Seleno-Aminopolysaccharide on the Intestinal Mucosal Oxidative Damage.

Zheng-Shun Wen, Zhen Tang, Li Ma, Tian-Long Zhu, You-Ming Wang, Xing-Wei Xiang, Bin Zheng

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  8. Article
  9. Review
  10. Oxidative medicine and cellular longevity · 2021
    Article
  11. Article
  12. Oxidative medicine and cellular longevity · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Zheng-Shun WenZhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food Science and Pharmaceutics, Zhejiang Ocean University, Zhoushan 316022, China. zswenmr@163.com.
Zhen TangZhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food Science and Pharmaceutics, Zhejiang Ocean University, Zhoushan 316022, China. tz19920904@126.com.
Li MaZhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food Science and Pharmaceutics, Zhejiang Ocean University, Zhoushan 316022, China. 15150512714@163.com.
Tian-Long ZhuDepartment of Agriculture, Jiaxing Vocational Technical College, Jiaxing 314036, China. tianlong4183@163.com.
You-Ming WangKey Laboratory of Animal Nutrition and Feed Science in East China, Ministry of Agriculture, College of Animal Science, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China. ymwang@zju.edu.cn.
Xing-Wei XiangZhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food Science and Pharmaceutics, Zhejiang Ocean University, Zhoushan 316022, China. xxw11086@126.com.
Bin ZhengZhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food Science and Pharmaceutics, Zhejiang Ocean University, Zhoushan 316022, China. 6369958@163.com.
Zhejiang Ocean University · CNJiaxing Vocational Technical College · CNZhejiang Marine Fisheries Research Institute · CNZhejiang University · CN

Funding

International Science & Technology Cooperation Program of China 2015DFA30980National Natural Science Foundation of China 31301982Zhejiang Provincial Key Research and Development Project of China 2019C02076Zhejiang Provincial Natural Science Foundation of China LY17C170001; LY18D060001Zhoushan Science and Technology Project of China 2018C21019
6 · The paper itself

Abstract

Low molecular weight seleno-aminopolysaccharide (LSA) is an organic selenium compound comprising selenium and low molecular weight aminopolysaccharide (LA), a low molecular weight natural linear polysaccharide derived from chitosan. LSA has been found to exert strong pharmacological activity. In this study, we aimed to investigate the protective effect of LSA on intestinal mucosal oxidative stress in a weaning piglet model by detecting the growth performance, intestinal mucosal structure, antioxidant indices, and expression level of intracellular transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) and its related factors. Our results indicated that LSA significantly increased the average daily gain and feed/gain (

Indexed as

Dietary SupplementsAnimalsAnimals, SucklingChitosanDiarrhea, InfantileDisease Models, AnimalHumansInfantIntestinal MucosaKelch-Like ECH-Associated Protein 1MaleMicroscopy, Electron, ScanningMolecular WeightNF-E2-Related Factor 2Oxidative StressSeleniumChitosanKelch-Like ECH-Associated Protein 1NF-E2-Related Factor 2Seleniumintestinal mucosalow molecular seleno-aminopolysaccharideNrf2–Keap1 pathwayoxidative damage

Identifiers

PMID30669387
PMCPMC6356751
OpenAlexW2909174303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.