ArticleSleep2019
Sleep and cognitive aging in the eighth decade of life.
Article in Sleep, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Impact of exercise intervention on depression, anxiety, sleep and quality of life in patients with cognitive impairment: a systematic review and network meta-analysis.Frontiers in psychiatry · 2025Pooled it
- Daytime Napping and Cognitive Health in Older Adults: A Systematic Review.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Pooled it
- Napping and cognitive decline: a systematic review and meta-analysis of observational studies.BMC geriatrics · 2022Pooled it
- The association between chronotype and incident dementia: exploring age, educational-attainment and sex differences.Epidemiology and psychiatric sciences · 2026Article
- Individual Sleep Problems Are Associated With an Accelerated Decline in Multiple Cognitive Functions in Older Adults.Journal of sleep research · 2025Article
- Chronotype as a potential risk factor for cognitive decline: The mediating role of sleep quality and health behaviours in a 10-year follow-up study.The journal of prevention of Alzheimer's disease · 2025Article
- Article
- Five-Year Changes in 24-Hour Sleep-Wake Activity and Dementia Risk in Oldest Old Women.Neurology · 2025Article
- Multidimensional frailty and sleep quality in late adulthood: A UK biobank examination.Journal of sleep research · 2025Article
- Using Polygenic Scores for Circadian Rhythms to Predict Wellbeing, Depressive Symptoms, Chronotype, and Health.Journal of biological rhythms · 2024Article
- Article
- Exome sequencing identifies genes associated with sleep-related traits.Nature human behaviour · 2024Article
- Sleep-Related Changes Prior to Cognitive Dysfunction.Current neurology and neuroscience reports · 2023Review
- Mental and physical health pathways linking insomnia symptoms to cognitive performance 14 years later.Sleep · 2023Article
- Disturbed sleep is associated with reduced verbal episodic memory and entorhinal cortex volume in younger middle-aged women with risk-reducing early ovarian removal.Frontiers in endocrinology · 2023Article
- Differential effects of chronotype on physical activity and cognitive performance in older adults.Frontiers in epidemiology · 2023Article
- Gender-and age-specific associations of sleep duration and quality with cognitive impairment in community-dwelling older adults in Anhui Province, China.Frontiers in public health · 2023Article
- Cognitive Function Trajectories and Factors among Chinese Older Adults with Subjective Memory Decline: CHARLS Longitudinal Study Results (2011-2018).International journal of environmental research and public health · 2022Article
- Does sleep duration moderate genetic and environmental contributions to cognitive performance?Sleep · 2022Article
- Sleep and Cognition: A Narrative Review Focused on Older Adults.Sleep medicine clinics · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 6 institutions in 1 country.
Funding
Abstract
We examined associations between self-reported sleep measures and cognitive level and change (age 70-76 years) in a longitudinal, same-year-of-birth cohort study (baseline N = 1091; longitudinal N = 664). We also leveraged GWAS summary data to ascertain whether polygenic scores (PGS) of chronotype and sleep duration related to self-reported sleep, and to cognitive level and change. Shorter sleep latency was associated with significantly higher levels of visuospatial ability, processing speed, and verbal memory (β ≥ |0.184|, SE ≤ 0.075, p ≤ 0.003). Longer daytime sleep duration was significantly associated slower processing speed (β = -0.085, SE = 0.027, p = 0.001), and with steeper 6-year decline in visuospatial reasoning (β = -0.009, SE = 0.003, p = 0.008), and processing speed (β = -0.009, SE = 0.002, p < 0.001). Only longitudinal associations between longer daytime sleeping and steeper cognitive declines survived correction for important health covariates and false discovery rate (FDR). PGS of chronotype and sleep duration were nominally associated with specific self-reported sleep characteristics for most SNP thresholds (standardized β range = |0.123 to 0.082|, p range = 0.003 to 0.046), but neither PGS predicted cognitive level or change following FDR. Daytime sleep duration is a potentially important correlate of cognitive decline in visuospatial reasoning and processing speed in older age, whereas cross-sectional associations are partially confounded by important health factors. A genetic propensity toward morningness and sleep duration were weakly, but consistently, related to self-reported sleep characteristics, and did not relate to cognitive level or change.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.