Evidence map›Paper›PMID 30668661›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2019

Characterization of Virus-specific Immune Response During Varicella Zoster Virus Encephalitis in a Young Adult.

Nicole L Sullivan, Christiane S Eberhardt, Andreas Wieland, Rama S Akondy, Jumi Yi, Anita K McElroy, Rafi Ahmed

Open access · greenAbstract readCase Reports
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Varicella zoster virus and the central nervous system.Nature reviews. Microbiology · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Nicole L SullivanEmory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia.
Christiane S EberhardtEmory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia.
Andreas WielandEmory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia.
Rama S AkondyEmory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia.
Jumi YiDepartment of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Georgia.
Anita K McElroyDepartment of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Georgia.
Rafi AhmedEmory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia.
Emory University · USUniversity of Geneva · CH

Funding

VACCINE INDUCED IMMUNITY IN THE YOUNG AND AGEDU19AI057266 · NIAID · EMORY UNIVERSITY · PI Rafi Ahmed · 2003 to 2026
$81.7M
Systems Biological Analysis of Innate and Adaptive Responses to VaccinationU19AI090023 · NIAID · EMORY UNIVERSITY · PI AHMED, RAFI, LI, SHUZHAO · 2010 to 2021
$45.0M
NIAID NIH HHS U19 AI057266NIAID NIH HHS U19 AI090023
6 · The paper itself

Abstract

An immunocompetent adult received corticosteroids for chest pain, which later was clinically found to be herpes zoster (HZ). She developed severe disease and rapid viral dissemination that elicited an exceptionally strong varicella zoster virus-specific B-cell and CD8 T-cell response. Clinicians should consider atypical HZ presentation prior to corticosteroid administration.

Indexed as

Adaptive ImmunityB-LymphocytesCD8-Positive T-LymphocytesEncephalitis, Varicella ZosterFemaleHerpesvirus 3, HumanHumansYoung AdultCD8 T cellsherpes zosterplasmablastsvaricella zoster virus

Identifiers

PMID30668661
PMCPMC7322817
OpenAlexW2908756711

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.