Evidence map›Paper›PMID 30668637›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2019

Frailty Screening Using the Electronic Health Record Within a Medicare Accountable Care Organization.

Nicholas M Pajewski, Kristin Lenoir, Brian J Wells, Jeff D Williamson, Kathryn E Callahan

Abstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Development and validation of an electronic health record-based frailty index in the UK Biobank.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  6. Blood pressure satisfaction and antihypertensive medication adherence effects frailty transitions in older hypertensive patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. External validation of an AI-based preoperative frailty index using real-world data.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  13. Article
  14. Long-Term Blood Pressure Variability and Physical Performance in Older Adults.Journal of clinical hypertension (Greenwich, Conn.) · 2025
    Observational
  15. Article
  16. Patient-reported pain severity is associated with shorter survival in older adults with newly diagnosed cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Article

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nicholas M PajewskiDepartment of Biostatistics and Data Science, Division of Public Health Sciences, Winston-Salem, North Carolina.
Kristin LenoirDepartment of Biostatistics and Data Science, Division of Public Health Sciences, Winston-Salem, North Carolina.
Brian J WellsDepartment of Biostatistics and Data Science, Division of Public Health Sciences, Winston-Salem, North Carolina.
Jeff D WilliamsonCenter for Health Care Innovation, Winston-Salem, North Carolina.
Kathryn E CallahanCenter for Health Care Innovation, Winston-Salem, North Carolina.

Funding

Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI STEPHEN B. KRITCHEVSKY · 2002 to 2026
$36.4M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Wake Forest Alzheimer's Disease Core CenterP30AG049638 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BAKER, LAURA D. · 2016 to 2020
$12.2M
Identifying Frailty in Primary Care: Implementation of an Electronic Medical Record-based Frailty IndexK76AG059986 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CALLAHAN, KATHRYN · 2018 to 2022
$1.2M
NCATS NIH HHS UL1 TR001420NIA NIH HHS K76 AG059986NIA NIH HHS P30 AG021332NIA NIH HHS P30 AG049638
6 · The paper itself

Abstract

backgroundThe accumulation of deficits model for frailty has been used to develop an electronic health record (EHR) frailty index (eFI) that has been incorporated into British guidelines for frailty management. However, there have been limited applications of EHR-based approaches in the United States.

methodsWe constructed an adapted eFI for patients in our Medicare Accountable Care Organization (ACO, N = 12,798) using encounter, diagnosis code, laboratory, medication, and Medicare Annual Wellness Visit (AWV) data from the EHR. We examined the association of the eFI with mortality, health care utilization, and injurious falls.

resultsThe overall cohort was 55.7% female, 85.7% white, with a mean age of 74.9 (SD = 7.3) years. In the prior 2 years, 32.1% had AWV data. The eFI could be calculated for 9,013 (70.4%) ACO patients. Of these, 46.5% were classified as prefrail (0.10 < eFI ≤ 0.21) and 40.1% frail (eFI > 0.21). Accounting for age, comorbidity, and prior health care utilization, the eFI independently predicted all-cause mortality, inpatient hospitalizations, emergency department visits, and injurious falls (all p < .001). Having at least one functional deficit captured from the AWV was independently associated with an increased risk of hospitalizations and injurious falls, controlling for other components of the eFI.

conclusionsConstruction of an eFI from the EHR, within the context of a managed care population, is feasible and can help to identify vulnerable older adults. Future work is needed to integrate the eFI with claims-based approaches and test whether it can be used to effectively target interventions tailored to the health needs of frail patients.

Indexed as

Accidental FallsAccountable Care OrganizationsAgedAged, 80 and overAge FactorsCohort StudiesElectronic Health RecordsFemaleFrailtyHospitalizationHumansLongitudinal StudiesMaleMass ScreeningMedicarePatient Acceptance of Health CareFallsFrailtyHealth ServicesMultimorbidities

Identifiers

PMID30668637
PMCPMC6777083

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.