ArticlePloS one2019
The prevalence of osteoarthritis: Higher risk after transfemoral amputation?-A database analysis with 1,569 amputees and matched controls.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Editorial: Advances in smart and adaptive prosthetic and wearable technologies.Frontiers in robotics and AI · 2026Article
- Prevalence, incidence, and progression of hip osteoarthritis in a young military population: The ADVANCE cohort study.Osteoarthritis and cartilage open · 2025Article
- A comparative study of limb load on the healthy side of above-knee amputees after reconstruction of assistive walking devices.Medicine · 2025Article
- [Motion analysis in Orthopaedic technology research].Unfallchirurgie (Heidelberg, Germany) · 2025Review
- Is Socket Flexion Alignment Associated With Changes in Gait Parameters in Individuals With an Above-knee Amputation and a Hip Flexion Contracture?Clinical orthopaedics and related research · 2025Observational
- Hip and knee replacement in lower limb amputees: a scoping review.BMC musculoskeletal disorders · 2024Article
- Compensatory gait mechanics in person with multiple toe amputation: A single case report.Clinical case reports · 2023Article
- Indications of musculoskeletal health in deceased male individuals with lower-limb amputations: comparison to non-amputee and diabetic controls.Scientific reports · 2023Article
- Walking asymmetry and its relation to patient-reported and performance-based outcome measures in individuals with unilateral lower limb loss.International biomechanics · 2022Article
- Ground reaction forces during double limb stances while walking in individuals with unilateral transfemoral amputation.Frontiers in bioengineering and biotechnology · 2022Article
- Symmetry function in gait pattern analysis in patients after unilateral transfemoral amputation using a mechanical or microprocessor prosthetic knee.Journal of neuroengineering and rehabilitation · 2021Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral studies have shown that patients with a unilateral amputation have an increased risk of developing osteoarthritis (OA) in the knee of their sound leg.
objectiveThe first objective was to investigate whether amputees are more frequently affected by gon-, cox- or polyarthritis as well as back pain or spinal disorders. We hypothesized that mobile and active transfemoral amputees more often experience OA and spinal disorders than non-amputees. The second objective was to compare the mean age of the patients with OA. PATIENTS: Patients with a unilateral transfemoral amputation (n = 1,569) and five abled-body control groups (each n = 1,569) matched in terms of age and gender resulting in total of 9,414 participants.
methodsGroups were analyzed regarding the prevalence of six selected diagnoses regarding musculoskeletal disorders.
resultsA significantly decreased prevalence of OA and specific disorders of the spine in transfemoral amputees compared to a control group was found. The amputees with OA are significantly younger than patients with OA in the control group.
conclusionThe results from the presented study contradict previously published literature. Apparently circumstances of life play an important role, like physical work and strenuous activities which are likely to be underrepresented in the amputee group. The results of the study need to be used cautiously due to the major limitation of the study which is the lack of detail in individual patients caused by the methodology.
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