Evidence map›Paper›PMID 30667359›Full record

ArticleeLife2019

Factors affecting template switch recombination associated with restarted DNA replication.

Manisha Jalan, Judith Oehler, Carl A Morrow, Fekret Osman, Matthew C Whitby

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. The Fission Yeast Mating-Type Switching Motto: "One-for-Two" and "Two-for-One".Microbiology and molecular biology reviews : MMBR · 2023
    Review
  6. Creation and resolution of non-B-DNA structural impediments during replication.Critical reviews in biochemistry and molecular biology · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. International journal of molecular sciences · 2021
    Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Manisha JalanDepartment of Biochemistry, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-4467-4934
Judith OehlerDepartment of Biochemistry, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-8397-6492
Carl A MorrowDepartment of Biochemistry, University of Oxford, Oxford, United Kingdom.
Fekret OsmanDepartment of Biochemistry, University of Oxford, Oxford, United Kingdom.
Matthew C WhitbyDepartment of Biochemistry, University of Oxford, Oxford, United Kingdom.ORCID 0000-0003-0951-3374
University of Oxford · GB

Funding

Biotechnology and Biological Sciences Research Council BB/P019706/1Medical Research Council MR/P028292/1Wellcome 090767/Z/09/Z
6 · The paper itself

Abstract

Homologous recombination helps ensure the timely completion of genome duplication by restarting collapsed replication forks. However, this beneficial function is not without risk as replication restarted by homologous recombination is prone to template switching (TS) that can generate deleterious genome rearrangements associated with diseases such as cancer. Previously we established an assay for studying TS in

Indexed as

Templates, GeneticBase PairingDNA ReplicationHomologous RecombinationMutationRNA, TransferSchizosaccharomycesSchizosaccharomyces pombe ProteinsRNA, TransferSchizosaccharomyces pombe Proteinschromosomesgene expressionhomologous recombinationrecombination-dependent replicationreplication fork barrierreplication fork collapseRTS1S. pombe

Identifiers

PMID30667359
PMCPMC6358216
OpenAlexW2911403014

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.