Evidence map›Paper›PMID 30667356›Full record

ArticleEmerging infectious diseases2019

Acute and Delayed Deaths after West Nile Virus Infection, Texas, USA, 2002-2012.

David C E Philpott, Melissa S Nolan, Nicole Evert, Bonny Mayes, Dawn Hesalroad, Eric Fonken, Kristy O Murray

Abstract readHistorical Article
In one paragraph

Article in Emerging infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Neuroinvasive West Nile virus infections after solid organ transplantation: Single center experience and systematic review.Transplant infectious disease : an official journal of the Transplantation Society · 2022
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David C E Philpott
Melissa S Nolan
Nicole Evert
Bonny Mayes
Dawn Hesalroad
Eric Fonken
Kristy O Murray

Funding

Renal And Neurological Outcomes In Chronically Infected West Nile Virus PatientsR01AI091816 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MURRAY, KRISTY · 2011 to 2014
$1.5M
NIAID NIH HHS R01 AI091816
6 · The paper itself

Abstract

Infection with West Nile virus (WNV) has a well-characterized acute disease process. However, long-term consequences are less understood. We searched death records for 4,142 residents of Texas, USA, infected with WNV during 2002-2012 and identified 557 (13%) deaths. We analyzed all-cause and cause-specific deaths after WNV infection by calculating standardized mortality ratios and using statewide mortality data. Acute-phase deaths (<90 days after symptom onset) occurred in 289 (7%) of case-patients; of those deaths, 289 (92%) were cases of West Nile neuroinvasive disease (WNND). Convalescent-phase deaths (>90 days after symptom onset) occurred in 268 (7%) of the remaining 3,853 case-patients; 210 (78%) of these deaths occurred in patients with WNND. Convalescent-phase WNND case-patients showed excess deaths from infectious and renal causes; case-patients <60 years of age had increased risk for all-cause death, specifically from renal, infectious, digestive, and circulatory causes. We provide population-level evidence of increased risk for death after WNV infection resulting in WNND.

Indexed as

West Nile virusAgedAged, 80 and overAge of OnsetCause of DeathFemaleHistory, 21st CenturyHumansKaplan-Meier EstimateMaleMiddle AgedProportional Hazards ModelsPublic Health SurveillanceTexasTime FactorsWest Nile Feveracute deathsdelayed deathshazard ratiosmeningitis/encephalitisstandardized mortality ratiossurvival analysisTexasUnited StatesvirusesWest Nile neuroinvasive diseaseWest Nile virusWNNDWNV

Identifiers

PMID30667356
PMCPMC6346437

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.