Evidence map›Paper›PMID 30667332›Full record

ReviewRadiology2019

Emerging Applications of Artificial Intelligence in Neuro-Oncology.

Jeffrey D Rudie, Andreas M Rauschecker, R Nick Bryan, Christos Davatzikos, Suyash Mohan

Abstract readReview
In one paragraph

Review in Radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

119 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  18. Toward diffusion MRI in the diagnosis and treatment of pancreatic cancer.Medical oncology (Northwood, London, England) · 2025
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59 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jeffrey D RudieFrom the Department of Radiology, Division of Neuroradiology, Perelman School of Medicine at the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104 (J.D.R., C.D., S.M.); Department of Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (A.M.R.); and Department of Diagnostic Medicine, Dell Medical School, University of Texas, Austin, Tex (R.N.B.).
Andreas M RauscheckerFrom the Department of Radiology, Division of Neuroradiology, Perelman School of Medicine at the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104 (J.D.R., C.D., S.M.); Department of Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (A.M.R.); and Department of Diagnostic Medicine, Dell Medical School, University of Texas, Austin, Tex (R.N.B.).
R Nick BryanFrom the Department of Radiology, Division of Neuroradiology, Perelman School of Medicine at the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104 (J.D.R., C.D., S.M.); Department of Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (A.M.R.); and Department of Diagnostic Medicine, Dell Medical School, University of Texas, Austin, Tex (R.N.B.).
Christos DavatzikosFrom the Department of Radiology, Division of Neuroradiology, Perelman School of Medicine at the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104 (J.D.R., C.D., S.M.); Department of Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (A.M.R.); and Department of Diagnostic Medicine, Dell Medical School, University of Texas, Austin, Tex (R.N.B.).
Suyash MohanFrom the Department of Radiology, Division of Neuroradiology, Perelman School of Medicine at the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104 (J.D.R., C.D., S.M.); Department of Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (A.M.R.); and Department of Diagnostic Medicine, Dell Medical School, University of Texas, Austin, Tex (R.N.B.).

Funding

RESEARCH TRACK RADIOLOGY RESIDENCYT32EB004311 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI Terence P Gade, Misun Hwang · 2005 to 2026
$4.5M
NIBIB NIH HHS T32 EB004311
6 · The paper itself

Abstract

Due to the exponential growth of computational algorithms, artificial intelligence (AI) methods are poised to improve the precision of diagnostic and therapeutic methods in medicine. The field of radiomics in neuro-oncology has been and will likely continue to be at the forefront of this revolution. A variety of AI methods applied to conventional and advanced neuro-oncology MRI data can already delineate infiltrating margins of diffuse gliomas, differentiate pseudoprogression from true progression, and predict recurrence and survival better than methods used in daily clinical practice. Radiogenomics will also advance our understanding of cancer biology, allowing noninvasive sampling of the molecular environment with high spatial resolution and providing a systems-level understanding of underlying heterogeneous cellular and molecular processes. By providing in vivo markers of spatial and molecular heterogeneity, these AI-based radiomic and radiogenomic tools have the potential to stratify patients into more precise initial diagnostic and therapeutic pathways and enable better dynamic treatment monitoring in this era of personalized medicine. Although substantial challenges remain, radiologic practice is set to change considerably as AI technology is further developed and validated for clinical use.

Indexed as

Artificial IntelligenceMagnetic Resonance ImagingPrecision MedicineAlgorithmsBiomarkers, TumorBrain NeoplasmsHumansRadiologyTumor MicroenvironmentBiomarkers, Tumor

Identifiers

PMID30667332
PMCPMC6389268

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.