Evidence map›Paper›PMID 30667237›Full record

ArticlePsychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors2019

Positive and negative reinforcement are differentially associated with alcohol consumption as a function of alcohol dependence.

Seung Bin Cho, Jinni Su, Sally I-Chun Kuo, Kathleen K Bucholz, Grace Chan, Howard J Edenberg, Vivia V McCutcheon, Marc A Schuckit, John R Kramer, Danielle M Dick

Abstract read
In one paragraph

Article in Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. A real-time exploration of the affect regulation hypothesis surrounding substance use.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026
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  18. A model of ethanol self-administration in head-fixed mice.Alcohol, clinical & experimental research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Seung Bin ChoDepartment of Psychology, Virginia Commonwealth University.ORCID 0000-0003-0336-6625
Jinni SuDepartment of Psychology, Virginia Commonwealth University.
Sally I-Chun KuoDepartment of Psychology, Virginia Commonwealth University.
Kathleen K BucholzDepartment of Psychiatry, Washington University at St. Louis.
Grace ChanDepartment of Psychiatry, University of Connecticut.
Howard J EdenbergDepartment of Biochemistry and Molecular Biology, Indiana University.
Vivia V McCutcheonDepartment of Psychiatry, Washington University at St. Louis.
Marc A SchuckitDepartment of Psychiatry, University of California at San Diego.
John R KramerDepartment of Psychiatry, University of Iowa.
Danielle M DickDepartment of Psychology, Virginia Commonwealth University.

Funding

Subject CollectionU10AA008401 · NIAAA · SUNY DOWNSTATE MEDICAL CENTER · PI JESSICA E SALVATORE · 1989 to 2026
$162.7M
Twin, molecular, and developmental approaches to understanding alcohol misuseK02AA018755 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI DICK, DANIELLE M · 2010 to 2019
$1.3M
National Institute of HealthNIAAA NIH HHS K02 AA018755NIAAA NIH HHS U10 AA008401
6 · The paper itself

Abstract

A multistage model of drug addiction in which individuals' motivations for use change as they develop problems is widely accepted; however, the evidence for this model comes mostly from animal work and cross-sectional studies. We used longitudinal data to test whether positive and negative reinforcement associated with alcohol consumption differed as a function of alcohol dependence (AD). Specifically, we tested whether (a) positive reinforcement is more strongly associated with alcohol consumption than is negative reinforcement among individuals without AD, (b) negative reinforcement is more strongly associated with AD than is positive reinforcement, and (c) in the presence of AD, the association between positive reinforcement and alcohol consumption becomes weaker, whereas the association with negative reinforcement becomes stronger. We included assessments between Ages 18 and 30 years from participants who indicated they ever had a drink (N = 2,556; 51.6% female) from the Collaborative Study on the Genetics of Alcoholism Prospective Study. Results from generalized estimating equations indicated that positive, but not negative, reinforcement was associated with alcohol consumption among individuals without AD. Both positive and negative reinforcement were associated with AD, but the association was stronger with negative reinforcement. Results from the multilevel growth model indicated that the association between negative reinforcement and alcohol consumption became stronger with the presence of AD, whereas the association between positive reinforcement and alcohol consumption did not differ as a function of AD. We provide empirical evidence that positive and negative reinforcement are differentially associated with alcohol consumption as a function of AD. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

Indexed as

Reinforcement, PsychologyAdolescentAdultAlcohol DrinkingAlcoholismFemaleHumansMaleMotivationProspective StudiesYoung Adult

Identifiers

PMID30667237
PMCPMC6459181

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.