ArticleMedical physics2019
Feasibility study of a point-of-care positron emission tomography system with interactive imaging capability.
Article in Medical physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Design of a Mobile and Electromagnetic Emissions-Compliant Brain Positron Emission Tomography (PET) Scanner.Sensors (Basel, Switzerland) · 2025Article
- Initial demonstration of the Scratch-PET concept: an intraoperative PET with a hand-held detector.Radiological physics and technology · 2025Article
- High-resolution Imaging Using Virtual-Pinhole PET Concept.PET clinics · 2024Review
- Multimodal laparoscopic coincidence gamma imaging system for near-infrared fluorescence guided surgery: a preclinical study.Journal of medical imaging (Bellingham, Wash.) · 2023Article
- 2D feasibility study of joint reconstruction of attenuation and activity in limited angle TOF-PET.IEEE transactions on radiation and plasma medical sciences · 2021Article
- Augmented Whole-Body Scanning via Magnifying PET.IEEE transactions on medical imaging · 2020Article
- A second-generation virtual-pinhole PET device for enhancing contrast recovery and improving lesion detectability of a whole-body PET/CT scanner.Medical physics · 2019Article
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Authors and funding
5 authors.
Funding
Abstract
purposeWe investigated the feasibility of a novel positron emission tomography (PET) system that provides near real-time feedback to an operator who can interactively scan a patient to optimize image quality. The system should be compact and mobile to support point-of-care (POC) molecular imaging applications. In this study, we present the key technologies required and discuss the potential benefits of such new capability.
methodsThe core of this novel PET technology includes trackable PET detectors and a fully three-dimensional, fast image reconstruction engine implemented on multiple graphics processing units (GPUs) to support dynamically changing geometry by calculating the system matrix on-the-fly using a tube-of-response approach. With near real-time image reconstruction capability, a POC-PET system may comprise a maneuverable front PET detector and a second detector panel which can be stationary or moved synchronously with the front detector such that both panels face the region-of-interest (ROI) with the detector trajectory contoured around a patient's body. We built a proof-of-concept prototype using two planar detectors each consisting of a photomultiplier tube (PMT) optically coupled to an array of 48 × 48 lutetium-yttrium oxyorthosilicate (LYSO) crystals (1.0 × 1.0 × 10.0 mm
resultsThe proof-of-concept prototype re-solves most of the spherical lesions despite a limited number of coincidence events and incomplete sampling. TOF information reduces artifacts in the reconstructed images. Systems with better timing resolution exhibit improved image quality and reduced artifacts. We observed a reconstruction speed of 0.96 × 10
conclusionsWe have developed GPU-based fast image reconstruction capability to support a PET system with arbitrary and dynamically changing geometry. Using TOF PET detectors, we demonstrated the feasibility of a PET system that can provide timely visual feedback to an operator who can scan a patient interactively to support POC imaging applications.
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