Evidence map›Paper›PMID 30666988›Full record

ReviewThe Indian journal of medical research2018

Nutrigenomics: Opportunities & challenges for public health nutrition.

V Sudhakar Reddy, Ravindranadh Palika, Ayesha Ismail, Raghu Pullakhandam, G Bhanuprakash Reddy

Open access · diamondAbstract readReview
In one paragraph

Review in The Indian journal of medical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Zinc: From Biological Functions to Therapeutic Potential.International journal of molecular sciences · 2023
    Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. In Pursuit of Healthy Aging: Effects of Nutrition on Brain Function.International journal of molecular sciences · 2021
    Review
  17. Review
  18. Review
  19. Nutrigenetics-personalized nutrition in obesity and cardiovascular diseases.International journal of obesity supplements · 2020
    Review
  20. Nutrigenomics in livestock-recent advances.Journal of applied genetics · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

V Sudhakar ReddyDepartment of Biochemistry, ICMR-National Institute of Nutrition, Hyderabad, India.
Ravindranadh PalikaDepartment of Biochemistry, ICMR-National Institute of Nutrition, Hyderabad, India.
Ayesha IsmailDepartment of Biochemistry, ICMR-National Institute of Nutrition, Hyderabad, India.
Raghu PullakhandamDepartment of Biochemistry, ICMR-National Institute of Nutrition, Hyderabad, India.
G Bhanuprakash ReddyDepartment of Biochemistry, ICMR-National Institute of Nutrition, Hyderabad, India.
National Institute of Nutrition · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hierarchical information flow through DNA-RNA-protein-metabolite collectively referred to as 'molecular fingerprint' defines both health and disease. Environment and food (quality and quantity) are the key factors known to affect the health of an individual. The fundamental concepts are that the transition from a healthy condition to a disease phenotype must occur by concurrent alterations in the genome expression or by differences in protein synthesis, function and metabolites. In other words, the dietary components directly or indirectly modulate the molecular fingerprint and understanding of which is dealt with nutrigenomics. Although the fundamental principles of nutrigenomics remain similar to that of traditional research, a collection of comprehensive targeted/untargeted data sets in the context of nutrition offers the unique advantage of understanding complex metabolic networks to provide a mechanistic understanding of data from epidemiological and intervention studies. In this review the challenges and opportunities of nutrigenomic tools in addressing the nutritional problems of public health importance are discussed. The application of nutrigenomic tools provided numerous leads on biomarkers of nutrient intake, undernutrition, metabolic syndrome and its complications. Importantly, nutrigenomic studies also led to the discovery of the association of multiple genetic polymorphisms in relation to the variability of micronutrient absorption and metabolism, providing a potential opportunity for further research toward setting personalized dietary recommendations for individuals and population subgroups.

Indexed as

Diet TherapyGene ExpressionHumansMetabolomicsMicronutrientsNutrigenomicsNutritional Physiological PhenomenaNutritional StatusPrecision MedicinePublic HealthMicronutrientsBiomarkersmicronutrientsmolecular fingerprintnutrigenomicsrecommended dietary allowancesstunting

Identifiers

PMID30666988
PMCPMC6366269
OpenAlexW2911244691

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.