Evidence map›Paper›PMID 30666820›Full record

Trial reportEuropean journal of heart failure2019

Potential role for interleukin-1 in the cardio-renal syndrome.

Leo F Buckley, Justin M Canada, Salvatore Carbone, Cory R Trankle, Dinesh Kadariya, Hayley Billingsley, George F Wohlford, Danielle L Kirkman, Antonio Abbate, Benjamin W Van Tassell

Open access · bronzeAbstract readLetterRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European journal of heart failure, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Mechanisms underlying atrial fibrillation in chronic kidney disease.Journal of molecular and cellular cardiology · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Leo F BuckleyDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Justin M CanadaVCU Pauley Heart Center, Richmond, VA, USA.
Salvatore CarboneVCU Pauley Heart Center, Richmond, VA, USA.
Cory R TrankleVCU Pauley Heart Center, Richmond, VA, USA.
Dinesh KadariyaVCU Pauley Heart Center, Richmond, VA, USA.
Hayley BillingsleyVCU Pauley Heart Center, Richmond, VA, USA.
George F WohlfordDepartment of Pharmacotherapy and Outcomes Science, Virginia Commonwealth University, Richmond, VA, USA.
Danielle L KirkmanDepartment of Kinesiology and Health Sciences, Virginia Commonwealth University, Richmond, VA, USA.
Antonio AbbateVCU Pauley Heart Center, Richmond, VA, USA.
Benjamin W Van TassellDepartment of Pharmacotherapy and Outcomes Science, Virginia Commonwealth University, Richmond, VA, USA.
Children's Hospital of Richmond at VCU · USVirginia Commonwealth University · USBrigham and Women's Hospital · US

Funding

Research Supplement to Promote Diversity in Health Related ResearchUL1TR002649 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2018 to 2022
$19.1M
Center for Clinical and Translational ResearchUL1TR000058 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2012 to 2015
$12.5M
Interleukin-1 blockade in recently decompensated heart failureR34HL117026 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI ABBATE, ANTONIO, VAN TASSELL, BENJAMIN W · 2013 to 2014
$671k
NCATS NIH HHS UL1 TR000058NCATS NIH HHS UL1TR000058NCATS NIH HHS UL1 TR002649NHLBI NIH HHS 1R34HL117026NHLBI NIH HHS R34 HL117026
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cardio-Renal SyndromeHeart FailureInterleukin-1Renal InsufficiencyFemaleHumansImmunosuppressive AgentsInflammationInterleukin 1 Receptor Antagonist ProteinKidney Function TestsMaleMiddle AgedMonitoring, ImmunologicTreatment OutcomeImmunosuppressive AgentsInterleukin-1Interleukin 1 Receptor Antagonist Protein

Identifiers

PMID30666820
PMCPMC6422755
OpenAlexW2912515290

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.