Evidence map›Paper›PMID 30666490›Full record

ReviewMolecular diversity2019

Aroyl and acyl cyanides as orthogonal protecting groups or as building blocks for the synthesis of heterocycles.

Kamal Usef Sadek, Ramadan Ahmed Mekheimer, Mohamed Abd-Elmonem, Mohamed Hilmy Elnagdi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular diversity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kamal Usef SadekChemistry Department, Faculty of Science, Minia University, Minia, 61519, Egypt. kusadek@yahoo.com.ORCID http://orcid.org/0000-0003-4342-5394
Ramadan Ahmed MekheimerChemistry Department, Faculty of Science, Minia University, Minia, 61519, Egypt.
Mohamed Abd-ElmonemChemistry Department, Faculty of Science, Minia University, Minia, 61519, Egypt.
Mohamed Hilmy ElnagdiChemistry Department, Faculty of Science, Cairo University, Giza, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

α-Cyanoketones represent a synthetically attractive scaffold possessing bifunctional reactivity which enabled synthesis of a diversity of products. This involves reaction of nucleophiles with electrophilic carbonyl carbon performing an efficient and regioselective way to acylation reaction, cycloaddition of activated cyano function with dipolarophiles, metal-catalyzed cross-dehydrogenative coupling carbocyanation across C-C multiple bonds as well as hydrocyanation. This review provides the recent developments in the chemistry of α-cyanoketones which will be beneficial for researchers and scientists in such field.

Indexed as

AcylationCyanidesCycloaddition ReactionHeterocyclic CompoundsCyanidesHeterocyclic CompoundsCarbocyanationCDC carbocyanationCycloaddition reactionRegioselective acylationα-Cyanoketones

Identifiers

PMID30666490

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.