Evidence map›Paper›PMID 30666317›Full record

ArticleAdvanced biosystems2018

Peptide Amphiphile Nanostructures for Targeting of Atherosclerotic Plaque and Drug Delivery.

Miranda M So, Neel A Mansukhani, Erica B Peters, Mazen S Albaghdadi, Zheng Wang, Charles M Rubert Pérez, Melina R Kibbe, Samuel I Stupp

Abstract read
In one paragraph

Article in Advanced biosystems, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Current Progress in Cross-Linked Peptide Self-Assemblies.International journal of molecular sciences · 2020
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Miranda M SoSimpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, IL 60611, USA.
Neel A MansukhaniSimpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, IL 60611, USA.
Erica B PetersDepartment of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Mazen S AlbaghdadiSimpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, IL 60611, USA.
Zheng WangDivision of Vascular Surgery, Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Charles M Rubert PérezSimpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, IL 60611, USA.
Melina R KibbeSimpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, IL 60611, USA.
Samuel I StuppSimpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, IL 60611, USA.

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Novel Vehicles for Targeted Cardiovascular RepairR01HL116577 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIBBE, MELINA RAE, STUPP, SAMUEL I · 2013 to 2016
$4.3M
Vascular Surgery Scientist Training ProgramT32HL094293 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ESKANDARI, MARK K · 2009 to 2023
$4.0M
NCATS NIH HHS UL1 TR001422NCI NIH HHS P30 CA016086NHLBI NIH HHS R01 HL116577NHLBI NIH HHS T32 HL094293
6 · The paper itself

Abstract

Co-assembled peptide amphiphile nanofibers designed to target atherosclerotic plaque and enhance cholesterol efflux are shown to encapsulate and deliver a liver X receptor agonist to increase efflux from murine macrophages

Indexed as

atherosclerosispeptidesself-assemblysupramolecular chemistry

Identifiers

PMID30666317
PMCPMC6338447

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.