Evidence map›Paper›PMID 30666185›Full record

ArticleFrontiers in molecular neuroscience2018

Transient Cognitive Impairment in Epilepsy.

Silvia Landi, Luigi Petrucco, Federico Sicca, Gian Michele Ratto

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Resting-state EEG markers of cognitive dysfunction in epilepsy: evidence from gamma power, alpha activity, and functional connectivity.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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  16. Article
  17. Cognitive Impairment in People with Epilepsy.Journal of clinical medicine · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Silvia LandiNEST, Istituto Nanoscienze-CNR and Scuola Normale Superiore, Pisa, Italy.
Luigi PetruccoGraduate School of Systemic Neurosciences, Ludwig Maximilian University of Munich (LMU), Munich, Germany.
Federico SiccaDepartment of Developmental Neuroscience, Fondazione IRCCS Stella Maris, Pisa, Italy.
Gian Michele RattoNEST, Istituto Nanoscienze-CNR and Scuola Normale Superiore, Pisa, Italy.
Istituto Nanoscienze · ITFondazione Stella Maris · ITLudwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Impairments of the dialog between excitation and inhibition (E/I) is commonly associated to neuropsychiatric disorders like autism, bipolar disorders and epilepsy. Moderate levels of hyperexcitability can lead to mild alterations of the EEG and are often associated with cognitive deficits even in the absence of overt seizures. Indeed, various testing paradigms have shown degraded performances in presence of acute or chronic non-ictal epileptiform activity. Evidences from both animal models and the clinics suggest that anomalous activity can cause cognitive deficits by transiently disrupting cortical processing, independently from the underlying etiology of the disease. Here, we will review our understanding of the influence of an abnormal EEG activity on brain computation in the context of the available clinical data and in genetic or pharmacological animal models.

Indexed as

animal models of epilepsycognitive impairment in mental disorderEEGepileptic encephalopathyinterictal epileptiform discharges

Identifiers

PMID30666185
PMCPMC6330286
OpenAlexW2909473965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.