Evidence map›Paper›PMID 30666170›Full record

ArticleOpen access emergency medicine : OAEM2019

Chronic fatigue syndrome in the emergency department.

Christian R Timbol, James N Baraniuk

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Open access emergency medicine : OAEM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03567811 (Exertional Exhaustion in Chronic Fatigue Syndrome), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03567811 nacompletednot on this map

Exertional Exhaustion in Chronic Fatigue Syndrome

TypeinterventionalSponsorGeorgetown UniversityRan2013 to 2018Enrolled72ConditionsChronic Fatigue SyndromeArmsSubmaximal bicycle exercise stress test on Days 1 and 2
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Recent research in myalgic encephalomyelitis/chronic fatigue syndrome: an evidence map.Health technology assessment (Winchester, England) · 2025
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Health system support among patients with ME/CFS in Switzerland.Journal of Taibah University Medical Sciences · 2023
    Article
  10. Article
  11. Article
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  13. Article
  14. Article
  15. Article
  16. Medical School Education on Myalgic Encephalomyelitis.Medicina (Kaunas, Lithuania) · 2021
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Christian R TimbolDivision of Rheumatology, Immunology and Allergy, Georgetown University, Washington, DC, USA, baraniuj@georgetown.edu.
James N BaraniukDivision of Rheumatology, Immunology and Allergy, Georgetown University, Washington, DC, USA, baraniuj@georgetown.edu.
Georgetown University · US

Funding

Exertional Exhaustion in CFSR01NS085131 · NINDS · GEORGETOWN UNIVERSITY · PI BARANIUK, JAMES N · 2013 to 2017
$1.7M
NINDS NIH HHS R01 NS085131
6 · The paper itself

Abstract

purposeChronic fatigue syndrome (CFS) is a debilitating disease characterized by fatigue, postexertional malaise, cognitive dysfunction, sleep disturbances, and widespread pain. A pilot, online survey was used to determine the common presentations of CFS patients in the emergency department (ED) and attitudes about their encounters.

methodsThe anonymous survey was created to score the severity of core CFS symptoms, reasons for going to the ED, and Likert scales to grade attitudes and impressions of care. Open text fields were qualitatively categorized to determine common themes about encounters.

resultsFifty-nine percent of respondents with physician-diagnosed CFS (total n=282) had gone to an ED. One-third of ED presentations were consistent with orthostatic intolerance; 42% of participants were dismissed as having psychosomatic complaints. ED staff were not knowledgeable about CFS. Encounters were unfavorable (3.6 on 10-point scale). The remaining 41% of subjects did not go to ED, stating nothing could be done or they would not be taken seriously. CFS subjects can be identified by a CFS questionnaire and the prolonged presence (>6 months) of unremitting fatigue, cognitive, sleep, and postexertional malaise problems.

conclusionThis is the first investigation of the presentation of CFS in the ED and indicates the importance of orthostatic intolerance as the most frequent acute cause for a visit. The self-report CFS questionnaire may be useful as a screening instrument in the ED. Education of ED staff about modern concepts of CFS is necessary to improve patient and staff satisfaction. Guidance is provided for the diagnosis and treatment of CFS in these challenging encounters.

Indexed as

myalgic encephalomyelitisorthostatic intolerancepatient satisfactionpostexertional malaiseSEIDsystemic exertion intolerance disease

Identifiers

PMID30666170
PMCPMC6333158
OpenAlexW2909612494

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.