Evidence map›Paper›PMID 30666096›Full record

ArticleClinical interventions in aging2019

Relationship between nutritional status and frailty in hospitalized older patients.

Xiufang Hong, Jing Yan, Liyu Xu, Shanshan Shen, Xingkun Zeng, Lingyan Chen

Abstract read
In one paragraph

Article in Clinical interventions in aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  9. Factors associated with frailty and the effect of frailty on postoperative outcomes in older adults with hip fracture.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiufang HongDepartment of Geriatrics, Zhejiang Hospital, Hangzhou 310013, People's Republic of China, zjicu@vip.163.com.
Jing YanDepartment of Geriatrics, Zhejiang Hospital, Hangzhou 310013, People's Republic of China, zjicu@vip.163.com.
Liyu XuDepartment of Geriatrics, Zhejiang Hospital, Hangzhou 310013, People's Republic of China, zjicu@vip.163.com.
Shanshan ShenDepartment of Geriatrics, Zhejiang Hospital, Hangzhou 310013, People's Republic of China, zjicu@vip.163.com.
Xingkun ZengDepartment of Geriatrics, Zhejiang Hospital, Hangzhou 310013, People's Republic of China, zjicu@vip.163.com.
Lingyan ChenDepartment of Geriatrics, Zhejiang Hospital, Hangzhou 310013, People's Republic of China, zjicu@vip.163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe definition of frailty still lacks quantitative biomarkers. This study aimed to investigate the relationship between nutrition-related biomarkers and frailty in hospitalized older patients. MATERIALS AND

methodsThis is a cross-sectional study including 380 hospitalized older patients. The patients were categorized as nonfrail (n=140), prefrail (n=81), and frail (n=159) by the criteria of frailty phenotype. The nutritional status was assessed using the mini nutritional assessment-short form (MNA-SF), levels of serum transferrin (TNF), prealbumin (PA), total protein (TP), albumin (ALB), retinol-binding protein (RBP), and hemoglobin (Hb).

resultsThe grip strength, levels of serum TFN, TP, ALB, Hb, and MNA-SF scores all decreased significantly in the order of nonfrail, prefrail, and frail groups (

conclusionHospitalized older patients with better nutritional status and higher levels of TFN, TP, and ALB were less likely to develop into frailty. These nutrition-related biomarkers may be used for the evaluation of nutritional status and frailty in older patients.

Indexed as

AgedAged, 80 and overBiomarkersComorbidityCross-Sectional StudiesFemaleFrail ElderlyFrailtyGeriatric AssessmentHumansMaleMalnutritionNutritional StatusNutrition AssessmentRisk AssessmentBiomarkerselderlyfrailtyfrailty phenotypemalnutritionnutrition

Identifiers

PMID30666096
PMCPMC6330965

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.