Observational studyBMC ophthalmology2019
Changes in choroidal thickness and optic nerve head morphology after filtering surgery: nonpenetrating deep sclerectomy versus trabeculectomy.
Observational study in BMC ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- A Prospective Evaluation of the 2-Year Efficacy and Safety of INTERCIL: A Novel Uveal Spacer for Open-Angle Glaucoma.Ophthalmology and therapy · 2026Article
- Evaluation of Posterior Segment Structural and Vascular Changes After Gonioscopy-Assisted Transluminal Trabeculotomy.Diagnostics (Basel, Switzerland) · 2026Article
- Longitudinal quantitative assessment of macular retinal and choroidal remodeling after trabeculectomy in chronic primary angle-closure glaucoma using ultra-widefield SS-OCTA.Scientific reports · 2025Observational
- Early evaluation of optic nerve head morphology and choroidal thickness after PreserFlo MicroShunt implantation.International ophthalmology · 2023Observational
- Efficacy and safety of deep sclerectomy with uveoscleral implant plus collagen matrix implant overcoming the superficial scleral flap in glaucoma surgery.International journal of ophthalmology · 2023Article
- Effect of SCUBA Diving on Ophthalmic Parameters.Medicina (Kaunas, Lithuania) · 2022Article
- Effect of pseudoexfoliation syndrome on lamina cribrosa morphology after uneventful phacoemulsification.International ophthalmology · 2022Article
- Relationship Between Changes in the Choroidal Structure and Blood Flow of the Macula After Trabeculectomy.Translational vision science & technology · 2021Article
- Long-term effects of trabeculectomy in primary open-angle glaucoma on segmented macular ganglion cell complex alterations.International ophthalmology · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to evaluate the changes in choroidal thickness and lamina cribrosa position after nonpenetrating deep sclerectomy (NPDS) and trabeculectomy.
methodsTwenty-three eyes with glaucoma that required filtering surgery were included (12 NDPS and 11 trabeculectomies) in this prospective observational study. OCT-enhanced depth imaging (OCT-EDI) was used to measure choroidal thickness, prelaminar tissue thickness and lamina cribrosa position before and 7 days and 1 month after surgery. All results are shown as median (interquartile range values).
resultsIntraocular pressure (IOP) was significantly lower 1 week after surgery than at baseline (7 (6/10) mmHg vs. 21 (18/26) mmHg; p < 0.001) with a mean 64% decrease. IOP remained significantly lower at 1 month with a 55% mean decrease as compared to baseline (10 (8/12) mmHg; p < 0.001). One week after surgery, the subfoveolar choroidal thickness (SFCT) significantly increased (372 (306/523) μm vs. 317 (227/413) μm; p = 0.04) and the prelaminar tissue (PLT) was significantly thicker (269 (162/360) μm vs. 138 (87/268) μm; p = 0.02) as compared to preoperative measurements. These changes were not statistically significant at one month. There were no differences concerning these parameters between the NPDS and trabeculectomy groups. During the first week, the SFCT increase was correlated with IOP reduction (r = - 0.41; p = 0.04).
conclusionsOCT-EDI allowed the visualization of structural changes at the level of the optic nerve and choroidal vascularization during acute IOP changes. No difference was observed between NPDS and trabeculectomy concerning these structural modifications.
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