Evidence map›Paper›PMID 30665366›Full record

ArticleBMC infectious diseases2019

Identfication of viral and bacterial etiologic agents of the pertussis-like syndrome in children under 5 years old hospitalized.

Stephanie Saiki-Macedo, Jorge Valverde-Ezeta, Angela Cornejo-Tapia, Maria Esther Castillo, Verónica Petrozzi-Helasvuo, Miguel Angel Aguilar-Luis, Luis J Del Valle, Erico Cieza-Mora, Carlos Bada, Olguita Del Aguila and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Stephanie Saiki-MacedoSchool of Medicine. Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Jorge Valverde-EzetaSchool of Medicine. Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Angela Cornejo-TapiaSchool of Medicine. Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Lima, Peru. angela.cornejo@upc.pe.
Maria Esther CastilloInstituto Nacional de Salud del Niño, Lima, Peru.
Verónica Petrozzi-HelasvuoSchool of Medicine. Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Miguel Angel Aguilar-LuisSchool of Medicine. Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Luis J Del ValleBarcelona Research Center for Multiscale Science and Engineering, Departament d'Enginyeria Química, EEBE, Universidad Politecnica de Catalunya (UPC), Barcelona Tech, Barcelona, Spain.
Erico Cieza-MoraHospita Regional Docente de Cajamarca, Cajamarca, Peru.
Carlos BadaHospital Nacional Edgardo Rebagliati Martins, Lima, Peru.
Olguita Del AguilaHospital de Emergencias Pediátricas, Lima, Peru.
Wilmer Silva-CasoSchool of Medicine. Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Johanna Martins-LunaSchool of Medicine. Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Fernando Vasquez-AchayaSchool of Medicine. Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Juana Del Valle-MendozaSchool of Medicine. Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Lima, Peru. juana.delvalle@upc.pe.
Peruvian University of Applied Sciences · PEInstituto de Investigación Nutricional · PEHospital Nacional Cayetano Heredia · PEInstituto Nacional de Salud del Niño · PENational University of Cajamarca · PEUniversitat Politècnica de Catalunya · ES

Funding

5th Incentive for Research of the Universidad Peruana de Ciencias Aplicadas EXP-10-2017-UPC
6 · The paper itself

Abstract

backgroundAcute respiratory infections (ARIs) represent an important cause of morbidity and mortality in children, remaining a major public health concern, especially affecting children under 5 years old from low-income countries. Unfortunately, information regarding their epidemiology is still limited in Peru.

methodsA secondary data analysis was performed from a previous cross-sectional study conducted in children with a probable diagnosis of Pertussis from January 2010 to July 2012. All samples were analyzed via Polymerase Chain Reaction (PCR) for the following etiologies: Influenza-A, Influenza-B, RSV-A, RSV-B, Adenovirus, Parainfluenza 1 virus, Parainfluenza 2 virus, Parainfluenza 3 virus, Mycoplasma pneumoniae and Chlamydia pneumoniae.

resultsA total of 288 patients were included. The most common pathogen isolated was Adenovirus (49%), followed by Bordetella pertussis (41%) from our previous investigation, the most prevelant microorganisms were Mycoplasma pneumonia (26%) and Influenza-B (19.8%). Coinfections were reported in 58% of samples and the most common association was found between B. pertussis and Adenovirus (12.2%).

conclusionsThere was a high prevalence of Adenovirus, Mycoplasma pneumoniae and other etiologies in patients with a probable diagnosis of pertussis. Despite the presence of persistent cough lasting at least two weeks and other clinical characteristics highly suspicious of pertussis, secondary etiologies should be considered in children under 5 years-old in order to give a proper treatment.

Indexed as

Adenoviridae InfectionsBordetella pertussisChild, PreschoolChlamydophila InfectionsChlamydophila pneumoniaeCoughCross-Sectional StudiesFemaleHospitalizationHumansInfantInfant, NewbornInfluenza, HumanMaleMycoplasma pneumoniaeParainfluenza Virus 3, HumanAcute respiratory infectionsAdenovirusBordetella pertussisMycoplasma pneumoniaePeru

Identifiers

PMID30665366
PMCPMC6341522
OpenAlexW2912093549

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.