Evidence map›Paper›PMID 30664881›Full record

ArticleBiochimica et biophysica acta. Biomembranes2019

Boundary lipids of the nicotinic acetylcholine receptor: Spontaneous partitioning via coarse-grained molecular dynamics simulation.

Liam Sharp, Reza Salari, Grace Brannigan

Abstract read
In one paragraph

Article in Biochimica et biophysica acta. Biomembranes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Tracking Membrane Protein Dynamics in Real Time.The Journal of membrane biology · 2021
    Review
  9. Article
  10. Article
  11. Essay on Biomembrane Structure.The Journal of membrane biology · 2019
    Review
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Liam SharpCenter for Computational and Integrative Biology, Rutgers University-Camden, Camden, NJ, United States of America.
Reza SalariCenter for Computational and Integrative Biology, Rutgers University-Camden, Camden, NJ, United States of America.
Grace BranniganCenter for Computational and Integrative Biology, Rutgers University-Camden, Camden, NJ, United States of America; Department of Physics, Rutgers University-Camden, Camden, NJ, United States of America. Electronic address: grace.brannigan@rutgers.edu.
Rutgers, The State University of New Jersey · US

Funding

X-ray and Neutron Interferometry Studies of Anesthetic Interactions with VoltageP01GM055876 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI ECKENHOFF, RODERIC G · 1997 to 2017
$22.4M
NIGMS NIH HHS P01 GM055876
6 · The paper itself

Abstract

Reconstituted nicotinic acetylcholine receptors (nAChRs) exhibit significant gain-of-function upon addition of cholesterol to reconstitution mixtures, and cholesterol affects the organization of nAChRs within domain-forming membranes, but whether nAChR partitions to cholesterol-rich liquid-ordered ("raft" or l

Indexed as

Molecular Dynamics SimulationTorpedo1,2-DipalmitoylphosphatidylcholineAnimalsCholesterolDocosahexaenoic AcidsFish ProteinsLipid BilayersReceptors, Nicotinic1,2-DipalmitoylphosphatidylcholineCholesterolcolfosceril palmitateDocosahexaenoic AcidsFish ProteinsLipid BilayersReceptors, NicotinicCholesterolDocosahexaenoic acid (DHA)Lipid-protein interactionsLipid raftsLiquid disorder (l(do))Liquid order (l(o))nAChR partitioningNicotinic acetylcholine receptorPolyunsaturated fatty acids (PUFA)

Identifiers

PMID30664881
PMCPMC6392067
OpenAlexW2884536260

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.