ReviewNature reviews. Microbiology2019
An evolving view of methane metabolism in the Archaea.
Review in Nature reviews. Microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 204 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
204 citing papers in PubMed, 580 citations in OpenAlex.
- Cobalt starvation affects multiple cellular processes inMicrobial genomics · 2026Article
- Phylogenetic reconciliation supports a methanogenic ancestor of the Archaea and a derived origin for host-associated lineages.Nature communications · 2026Article
- Metagenomic Insights Into Red Sea Biodiversity Across the Web of Life.Environmental microbiology · 2026Article
- Insights Gained by High-throughput Chromosome Conformation Capture (Hi-C) into the Viral Modulation of Methane Production in Anaerobic Digestion.Environmental science & technology · 2026Article
- Vegetation Increases CHGlobal change biology · 2026Article
- Diversity, ecology, cell biology and evolution of the Asgard archaea.Nature reviews. Microbiology · 2026Review
- Organic carbon oxidation state shapes fermentative methanogenic microbiomes and controls greenhouse gas fluxes.Nature communications · 2026Article
- Patterns and drivers of macro- and micro-diversity of mudflat intertidal archaeomes along the Chinese coasts.mSystems · 2026Article
- Carbon monoxide metabolism in freshwater anaerobic methanotrophic archaea.Nature communications · 2026Article
- Backbone Thioamidation of a Ribosomal Subunit Protein in Pseudomonadota.Biochemistry · 2026Article
- Comparison of Gut Microbiota and Metabolic Characteristics Between Miechongshu-Treated and Untreated Yili Horses.Animals : an open access journal from MDPI · 2026Article
- Metagenomic analysis of fecal microbiomes reveals genetic potential for diverse hydrogen management strategies in marsupials.mSystems · 2026Article
- Elevated microbial network complexity and enriched methanogens contribute to higher methanogenic potential in hollows than in hummocks in alpine meadows.Environmental microbiome · 2026Article
- Synthetic Biology of Plants and Microbes for Agriculture, Environment, and Future Applications.Chemical reviews · 2026Review
- Intracellular accumulation of hydrophobic 1,3-PDN inhibits methanogenesis in rumen methanogens.The ISME journal · 2026Article
- Rice gs3 allele and low-nitrogen conditions enrich rhizosphere microbiota that mitigate methane emissions and promote beneficial crop traits.The ISME journal · 2026Article
- Phylogenetic assembly of methanogenesis regulates methane yield in food-waste anaerobic digestion.The ISME journal · 2026Article
- Biowaste-grown live microbial feed additive sustainably and significantly cut enteric methane emissions in Indian livestock.Scientific reports · 2026Article
- A genomic view of Earth's biomes.Nature reviews. Genetics · 2026Review
- Methane-cycling microbial communities are spatially structured, seasonally dynamic, and functionally coupled in sediments of two nearby eutrophic hydroelectric reservoirs.Frontiers in microbiology · 2026Article
144 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Methane is a key compound in the global carbon cycle that influences both nutrient cycling and the Earth's climate. A limited number of microorganisms control the flux of biologically generated methane, including methane-metabolizing archaea that either produce or consume methane. Methanogenic and methanotrophic archaea belonging to the phylum Euryarchaeota share a genetically similar, interrelated pathway for methane metabolism. The key enzyme in this pathway, the methyl-coenzyme M reductase (Mcr) complex, catalyses the last step in methanogenesis and the first step in methanotrophy. The discovery of mcr and divergent mcr-like genes in new euryarchaeotal lineages and novel archaeal phyla challenges long-held views of the evolutionary origin of this metabolism within the Euryarchaeota. Divergent mcr-like genes have recently been shown to oxidize short-chain alkanes, indicating that these complexes have evolved to metabolize substrates other than methane. In this Review, we examine the diversity, metabolism and evolutionary history of mcr-containing archaea in light of these recent discoveries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.