Evidence map›Paper›PMID 30664660›Full record

ArticleScientific reports2019

Rescue of hematopoietic stem/progenitor cells formation in plcg1 zebrafish mutant.

Karine F Ferri-Lagneau, Jamil Haider, Shengmin Sang, TinChung Leung

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Effects of Ginger (Biomolecules · 2024
    Review
  2. Polyphenol-Rich Ginger (Molecules (Basel, Switzerland) · 2022
    Review
  3. An assessment of vaping-induced inflammation and toxicity: A feasibility study using a 2-stage zebrafish and mouse platform.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2022
    Article
  4. Biomechanical cues as master regulators of hematopoietic stem cell fate.Cellular and molecular life sciences : CMLS · 2021
    Review
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Karine F Ferri-LagneauThe Biomedical/Biotechnology Research Institute, North Carolina Central University, North Carolina Research Campus, Nutrition Research Building, Kannapolis, NC, 28081, USA.
Jamil HaiderThe Biomedical/Biotechnology Research Institute, North Carolina Central University, North Carolina Research Campus, Nutrition Research Building, Kannapolis, NC, 28081, USA.
Shengmin SangLaboratory for Functional Foods and Human Health, Center for Excellence in Post-Harvest Technologies, North Carolina A&T State University, North Carolina Research Campus, Nutrition Research Building, Kannapolis, NC, 28081, USA.
TinChung LeungThe Biomedical/Biotechnology Research Institute, North Carolina Central University, North Carolina Research Campus, Nutrition Research Building, Kannapolis, NC, 28081, USA. tleung@nccu.edu.
North Carolina Central University · USNorth Carolina Agricultural and Technical State University · US

Funding

Understanding Perceptions of HIV Risk, PrEP, and PrEP use among African American Women Attending an HBCUU54MD012392 · NIMHD · NORTH CAROLINA CENTRAL UNIVERSITY · PI Cherise Baldwin Harrington · 2017 to 2026
$38.1M
Targeting the MEKK2-ERK5 Signaling Node in Triple Negative Breast CancerU54CA156735 · NCI · NORTH CAROLINA CENTRAL UNIVERSITY · PI RICHARDSON, MICHELER RICARDO · 2010 to 2021
$13.0M
Targeting the MEKK2-ERK5 Signaling Node in Triple Negative Breast CancerU54CA156733 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI EARP, H. SHELTON · 2010 to 2020
$9.7M
NCI NIH HHS U54 CA156733NIMHD NIH HHS U54 MD012392
6 · The paper itself

Abstract

Hematopoietic stem/progenitor cells (HSPC) in zebrafish emerge from the aortic hemogenic endothelium (HE) and migrate towards the caudal hematopoietic tissue (CHT), where they expand and differentiate during definitive hematopoiesis. Phospholipase C gamma 1 (Plcγ1) has been implicated for hematopoiesis in vivo and in vitro and is also required to drive arterial and HSPC formation. Genetic mutation in plcg1

Indexed as

HematopoiesisAnimalsAnimals, Genetically ModifiedBone Morphogenetic ProteinsCatecholsFatty AlcoholsHemangioblastsHematopoietic Stem CellsMutationPhospholipase C gammaPlant ExtractsReceptors, NotchZebrafishZebrafish ProteinsZingiber officinaleBone Morphogenetic ProteinsCatecholsFatty AlcoholsgingerolPhospholipase C gammaPlant ExtractsReceptors, NotchZebrafish Proteins

Identifiers

PMID30664660
PMCPMC6341084
OpenAlexW2910935804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.