ArticleNature communications2019
C1 CAGE detects transcription start sites and enhancer activity at single-cell resolution.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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Who cites it
61 citing papers in PubMed.
- Directionality of transcriptional regulatory elements.Nature communications · 2026Article
- Protocol for simultaneous profiling of transcription start sites and full-length transcripts from low-input samples using Smart-seq+5'.STAR protocols · 2026Article
- Accurate profiling of single-cell alternative transcript start sites by correcting RNA degradation.Nature communications · 2026Article
- Defining the Cis-Regulatory Elements of SCN1A in GABAergic Interneurons.Molecular neurobiology · 2025Article
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- The developmental factor TBX3 engages with the Wnt/β-catenin transcriptional complex in colorectal cancer to regulate metastasis genes.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Sequencing technologies to measure translation in single cells.Nature reviews. Molecular cell biology · 2025Review
- Advances and applications in single-cell and spatial genomics.Science China. Life sciences · 2025Review
- Predicting and comparing transcription start sites in single cell populations.PLoS computational biology · 2025Article
- Applications of single‑cell omics and spatial transcriptomics technologies in gastric cancer (Review).Oncology letters · 2024Review
- The level of protein in the maternal murine diet modulates the facial appearance of the offspring via mTORC1 signaling.Nature communications · 2024Article
- The diagnostic efficacy of seven autoantibodies in early detection of ground-glass nodular lung adenocarcinoma.Frontiers in oncology · 2024Article
- Single-cell analysis of the epitranscriptome: RNA modifications under the microscope.RNA biology · 2024Review
- CamoTSS: analysis of alternative transcription start sites for cellular phenotypes and regulatory patterns from 5' scRNA-seq data.Nature communications · 2023Article
- From Genotype to Phenotype: How Enhancers Control Gene Expression and Cell Identity in Hematopoiesis.HemaSphere · 2023Review
- Dosage compensation of Z sex chromosome genes in avian fibroblast cells.Genome biology · 2023Article
- Article
- Positional influence on cellular transcriptional identity revealed through spatially segmented single-cell transcriptomics.Cell systems · 2023Article
- Decoding enhancer complexity with machine learning and high-throughput discovery.Genome biology · 2023Review
1 more citing papers are in PubMed but not listed here.
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Authors and funding
26 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Single-cell transcriptomic profiling is a powerful tool to explore cellular heterogeneity. However, most of these methods focus on the 3'-end of polyadenylated transcripts and provide only a partial view of the transcriptome. We introduce C1 CAGE, a method for the detection of transcript 5'-ends with an original sample multiplexing strategy in the C1
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