Evidence map›Paper›PMID 30664265›Full record

ArticleAmerican journal of primatology2019

Cross-sectional comparison of health-span phenotypes in young versus geriatric marmosets.

Corinna N Ross, Jessica Adams, Olga Gonzalez, Edward Dick, Luis Giavedoni, Vida L Hodara, Kimberley Phillips, Anna D Rigodanzo, Balakuntalam Kasinath, Suzette D Tardif

Abstract readComparative Study
In one paragraph

Article in American journal of primatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Wild capuchin monkeys as a model system for investigating the social and ecological determinants of ageing.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
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  10. Reuniting the Body "Neck Up and Neck Down" to Understand Cognitive Aging: The Nexus of Geroscience and Neuroscience.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  11. Article
  12. Hydrogen Sulfide and the Kidney.Advances in experimental medicine and biology · 2021
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  14. Differential ageing trajectories in motivation, inhibitory control and cognitive flexibility in Barbary macaques (Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Corinna N RossDepartment of Science and Mathematics, Texas A&M University San Antonio, San Antonio, Texas.ORCID 0000-0003-0299-2069
Jessica AdamsSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas.
Olga GonzalezSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas.
Edward DickSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas.
Luis GiavedoniSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas.
Vida L HodaraSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas.
Kimberley PhillipsDepartment of Psychology, Trinity University, San Antonio, Texas.ORCID 0000-0002-5517-3596
Anna D RigodanzoDepartment of Psychology, Trinity University, San Antonio, Texas.
Balakuntalam KasinathBarshop Institute for Longevity and Aging Studies, University of Texas Health San Antonio, San Antonio, Texas.
Suzette D TardifSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas.ORCID 0000-0002-3412-7742
Texas Biomedical Research Institute · USTrinity University · USThe University of Texas Health Science Center at San Antonio · US

Funding

The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
San Antonio OAIC - Research Education Component (REC)P30AG044271 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Adam Salmon, Elena Volpi · 2015 to 2026
$14.1M
NIA NIH HHS P30 AG044271NIH HHS P51 OD011133Texas Biomedical Research Institute
6 · The paper itself

Abstract

The development of the marmoset as a translational model for healthspan and lifespan studies relies on the characterization of health parameters in young and geriatric marmosets. This cross-sectional study examined health phenotypes in marmosets for five domains of interest for human health and aging: mobility, cognition, metabolism, homeostasis, and immune function. Geriatric marmosets were found to have significant executive function impairment when compared to young animals. While geriatric animals did not show gross abnormalities in mobility and measures of locomotion, their types of movement were altered from young animals. Geriatric marmosets had alterations in cardiac function, with significantly increased mean arterial pressures; metabolism, with significantly lower VO

Indexed as

AgingHealth StatusAnimalsCallithrixCognitionCross-Sectional StudiesFemaleHomeostasisMaleMobility LimitationModels, AnimalPhenotypeanimal modelsbiomarkers of aginghealthspanlongevitynonhuman primates

Identifiers

PMID30664265
PMCPMC7036287
OpenAlexW2913448723

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.