Evidence map›Paper›PMID 30664116›Full record

ArticleJournal of computer assisted tomography

Radiomics for Classifying Histological Subtypes of Lung Cancer Based on Multiphasic Contrast-Enhanced Computed Tomography.

Linning E, Lin Lu, Li Li, Hao Yang, Lawrence H Schwartz, Binsheng Zhao

Abstract read
In one paragraph

Article in Journal of computer assisted tomography. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  16. Feature selection methods and predictive models in CT lung cancer radiomics.Journal of applied clinical medical physics · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Linning E
Lin LuDepartment of Radiology, Columbia University Medical Center, New York, NY.
Li LiDepartment of Pathology, Shanxi DAYI Hospital, Taiyuan, Shanxi, China.
Hao YangDepartment of Radiology, Columbia University Medical Center, New York, NY.
Lawrence H SchwartzDepartment of Radiology, Columbia University Medical Center, New York, NY.
Binsheng ZhaoDepartment of Radiology, Columbia University Medical Center, New York, NY.

Funding

Integrating Radiomics into S0819 and Lung-MAP, Biomarker Driven Clinical Trials for Lung CancerU01CA225431 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI SCHWARTZ, LAWRENCE H, ZHAO, BINSHENG · 2018 to 2022
$3.1M
NCI NIH HHS U01 CA225431
6 · The paper itself

Abstract

objectivesThe aim of this study was to evaluate the performance of the radiomics method in classifying lung cancer histological subtypes based on multiphasic contrast-enhanced computed tomography (CT) images.

methodsA total of 229 patients with pathologically confirmed lung cancer were retrospectively recruited. All recruited patients underwent nonenhanced and dual-phase chest contrast-enhanced CT; 1160 quantitative radiomics features were calculated to build a radiomics classification model. The performance of the classification models was evaluated by the receiver operating characteristic curve.

resultsThe areas under the curve of radiomics models in classifying adenocarcinoma and squamous cell carcinoma, adenocarcinoma and small cell lung cancer, and squamous cell carcinoma and small cell lung cancer were 0.801, 0.857, and 0.657 (nonenhanced); 0.834, 0.855, and 0.619 (arterial phase); and 0.864, 0.864, and 0.664 (venous phase), respectively. Moreover, the application of contrast-enhanced CT may affect the selection of radiomics features.

conclusionsOur study indicates that radiomics may be a promising tool for noninvasive predicting histological subtypes of lung cancer based on the multiphasic contrast-enhanced CT images.

Indexed as

Contrast MediaAdenocarcinoma of LungAgedAged, 80 and overCarcinoma, Squamous CellDiagnosis, DifferentialFemaleHumansIohexolLungLung NeoplasmsMaleMiddle AgedRadiographic Image EnhancementRetrospective StudiesSmall Cell Lung CarcinomaContrast MediaIohexol

Identifiers

PMID30664116
PMCPMC6527094

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.