Evidence map›Paper›PMID 30664057›Full record

ReviewAnesthesiology2019

Imaging the Injured Lung: Mechanisms of Action and Clinical Use.

Maurizio Cereda, Yi Xin, Alberto Goffi, Jacob Herrmann, David W Kaczka, Brian P Kavanagh, Gaetano Perchiazzi, Takeshi Yoshida, Rahim R Rizi

Erratum issuedOpen access · bronzeAbstract readReview
In one paragraph

Review in Anesthesiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Dead space in critical care: a practical approach with clinical scenarios.Journal of anesthesia, analgesia and critical care · 2026
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Observational
  14. Article
  15. Review
  16. Article
  17. Imaging the Lung in ARDS: A Primer.Respiratory care · 2024
    Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Maurizio CeredaFrom the Department of Anesthesiology and Critical Care and the Department of Radiology (M.C., Y.X., R.R.R.), University of Pennsylvania, Philadelphia, Pennsylvania the Interdepartmental Division of Critical Care Medicine and Department of Medicine (A.G.) Hospital for Sick Children (B.P.K., T.Y.), University of Toronto, Toronto, Ontario, Canada the Departments of Anesthesia and Biomedical Engineering (J.H.) Anesthesia, Radiology, and Biomedical Engineering (D.W.K.), University of Iowa, Iowa City, Iowa the Hedenstierna Laboratory and Uppsala University Hospital, Uppsala University, Uppsala, Sweden (G.P.).
Yi Xin
Alberto Goffi
Jacob Herrmann
David W Kaczka
Brian P Kavanagh
Gaetano Perchiazzi
Takeshi Yoshida
Rahim R Rizi
Hospital for Sick Children · CAUniversity of Pennsylvania · US

Funding

Multi-center Structural & Functional Quantitative CT Pulmonary PhenotypingR01HL112986 · NHLBI · UNIVERSITY OF IOWA · PI HOFFMAN, ERIC ALFRED · 2012 to 2016
$4.6M
Defining the role of early pulmonary vascular disease in COPDR01HL126838 · NHLBI · UNIVERSITY OF IOWA · PI HAN, MEILAN K, HOFFMAN, ERIC ALFRED · 2015 to 2018
$3.1M
An Integrated Approach to Predict and Improve the Outcomes of Lung InjuryR01HL137389 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CEREDA, MAURIZIO FRANCO · 2018 to 2021
$3.0M
Assessment of Lung Injury with integrated Imaging TechniquesR01HL139066 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI RIZI, RAHIM R · 2017 to 2020
$2.4M
NHLBI NIH HHS R01 HL112986NHLBI NIH HHS R01 HL126838NHLBI NIH HHS R01 HL137389NHLBI NIH HHS R01 HL139066
6 · The paper itself

Abstract

Acute respiratory distress syndrome (ARDS) consists of acute hypoxemic respiratory failure characterized by massive and heterogeneously distributed loss of lung aeration caused by diffuse inflammation and edema present in interstitial and alveolar spaces. It is defined by consensus criteria, which include diffuse infiltrates on chest imaging-either plain radiography or computed tomography. This review will summarize how imaging sciences can inform modern respiratory management of ARDS and continue to increase the understanding of the acutely injured lung. This review also describes newer imaging methodologies that are likely to inform future clinical decision-making and potentially improve outcome. For each imaging modality, this review systematically describes the underlying principles, technology involved, measurements obtained, insights gained by the technique, emerging approaches, limitations, and future developments. Finally, integrated approaches are considered whereby multimodal imaging may impact management of ARDS.

Indexed as

HumansLungRespiratory Distress SyndromeTomography, X-Ray Computed

Identifiers

PMID30664057
PMCPMC6692186
OpenAlexW3092031531

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.