Evidence map›Paper›PMID 30663130›Full record

ArticleJournal of the European Academy of Dermatology and Venereology : JEADV2019

Utilization of the validated Psoriasis Epidemiology Screening Tool to identify signs and symptoms of psoriatic arthritis among those with psoriasis: a cross-sectional analysis from the US-based Corrona Psoriasis Registry.

P J Mease, J B Palmer, P Hur, B E Strober, M Lebwohl, C Karki, G W Reed, C J Etzel, J D Greenberg, P S Helliwell

Open access · hybridAbstract read
In one paragraph

Article in Journal of the European Academy of Dermatology and Venereology : JEADV, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

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  19. [Psoriatic arthritis: important aspects for the dermatological practice].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 3 countries.

P J MeaseSwedish Medical Center, University of Washington, Seattle, WA, USA.
J B PalmerNovartis Pharmaceuticals Corporation, East Hanover, NJ, USA.
P HurNovartis Pharmaceuticals Corporation, East Hanover, NJ, USA.
B E StroberUniversity of Connecticut Health Center, Farmington, CT, USA.
M LebwohlIcahn School of Medicine at Mount Sinai, New York, NY, USA.
C KarkiCorrona, LLC, Waltham, MA, USA.
G W ReedCorrona, LLC, Waltham, MA, USA.
C J EtzelCorrona, LLC, Waltham, MA, USA.
J D GreenbergCorrona, LLC, Waltham, MA, USA.
P S HelliwellUniversity of Leeds, Leeds, UK.
Novartis (United States) · USOptron Systems (United States) · USIcahn School of Medicine at Mount Sinai · USNew York University · USProbity Medical Research · CASwedish Medical Center · USUniversity of Leeds · GBUniversity of Massachusetts Chan Medical School · US

Funding

AbbVieAmgenBoehringer IngelheimBristol-Myers SquibbCrescendoEli Lilly and CompanyGenentechGileadGSKHorizon Pharma USAJanssenMerckMomenta PharmaceuticalsNovartisPfizer IncRocheUCBValeant
6 · The paper itself

Abstract

backgroundDespite increasing awareness of the disease, rates of undiagnosed psoriatic arthritis (PsA) are high in patients with psoriasis (PsO). The validated Psoriasis Epidemiology Screening Tool (PEST) is a five-item questionnaire developed to help identify PsA at an early stage.

objectivesTo assess the risk of possible undiagnosed PsA among patients with PsO and characterize patients based on PEST scores.

methodsThis study included all patients enrolled in the Corrona PsO Registry with data on all five PEST questions. Demographics, clinical characteristics and patient-reported outcomes were compared in Corrona PsO Registry patients with PEST scores ≥3 and <3 using t-tests for continuous variables and chi-squared tests for categorical variables; scores ≥3 may indicate PsA.

resultsOf 1516 patients with PsO, 904 did not have dermatologist-reported PsA; 112 of these 904 patients (12.4%) scored ≥3 and were significantly older, female, less likely to be working, and had higher BMI than patients with scores <3. They also had significantly longer PsO duration, were more likely to have nail PsO and had worse health status, pain, fatigue, Dermatology Life Quality Index and activity impairment.

conclusionsImproved PsA screening is needed in patients with PsO because the validated PEST identified over one-tenth of registry patients who were not noted to have PsA as having scores ≥3, who could have had undiagnosed PsA. Appropriate, earlier care is important because these patients were more likely to have nail PsO, worse health-related quality of life and worse activity impairment.

Indexed as

RegistriesAdultAgedArthritis, PsoriaticCross-Sectional StudiesFemaleHumansMaleMiddle AgedPsoriasisReproducibility of ResultsUnited States

Identifiers

PMID30663130
PMCPMC6593969
OpenAlexW2913092006

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.