ArticleDevelopmental medicine and child neurology2019
Prevalence of metabolic syndrome and cardiovascular disease risk factors in adults with cerebral palsy.
Article in Developmental medicine and child neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- Immersive virtual reality arm exercise, physical activity, and cardiometabolic health in cerebral palsy: A phase 1 trial.Developmental medicine and child neurology · 2026Article
- Circulating mitochondrial-derived microproteins at rest and in response to an acute bout of endurance exercise in individuals with cerebral palsy.Experimental physiology · 2026Article
- Feasibility of Vigorous Extended Reality Tele-Exergaming for Cardiometabolic Health in Youth With Mobility Disabilities: Protocol for a Case Series Study.JMIR research protocols · 2026Article
- Sprint-Intensity Arm Interval Training May Improve Cardiorespiratory Fitness and Cardiometabolic Health Among Children With Mobility Disabilities: Case Report.JMIR formative research · 2025Article
- Relationship between nutritional assessment and nutritional risk screening in hospitalized children with cerebral palsy: a single-center prospective study.Scientific reports · 2025Article
- Article
- School-Based Virtual Reality Programming for Obtaining Moderate-Intensity Exercise Among Children With Disabilities: Pre-Post Feasibility Study.JMIR formative research · 2025Article
- 2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2025Review
- Effects of multicomponent exercise intervention on cardiometabolic risk factors in children and young adults with cerebral palsy: a multiple-baseline trial.BMC sports science, medicine & rehabilitation · 2024Article
- Impact of Serial Casting on Autonomic Nervous System Responses during Virtual Reality Tasks in Children with Cerebral Palsy: A Pilot Study Comparing Orthoses and Barefoot Conditions.Brain sciences · 2024Article
- Comorbidity Clusters Among Adults With Cerebral Palsy: A Latent Class Analysis.American journal of preventive medicine · 2024Article
- Telehealth Movement-to-Music With Arm-Based Sprint-Intensity Interval Training to Improve Cardiometabolic Health and Cardiorespiratory Fitness in Children With Cerebral Palsy: Protocol for a Pilot Randomized Controlled Trial.JMIR research protocols · 2024Article
- 2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2024Review
- Association between healthy eating index-2015 scores and metabolic syndrome among Iranian women: a cross-sectional study.BMC women's health · 2024Article
- Children with bilateral cerebral palsy use their hip joint to complete a step-up task.Frontiers in human neuroscience · 2024Article
- Article
- Potential use of salivary TNF-α as a vaccine-induced pain biomarker in people with cerebral palsy and communication disorders.PloS one · 2024Article
- Low skeletal muscle mass and liver fibrosis in children with cerebral palsy.European journal of pediatrics · 2023Article
- Tools for Nutrition Assessment of Adults with Cerebral Palsy: Development of a Gold Standard.Current nutrition reports · 2023Review
- Quantitative measures of motor development in Angelman syndrome.American journal of medical genetics. Part A · 2023Article
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the prevalence of metabolic syndrome and cardiovascular disease (CVD) risk factors and the association between common metabolic markers and Gross Motor Function Classification System (GMFCS) levels in ambulatory adults with cerebral palsy (CP).
methodMetabolic markers and GMFCS levels were evaluated in a cross-sectional study of 70 ambulatory adults with CP (34 males, 36 females; mean age 24y 5mo [SD 5y 4mo], range 18y 6mo-48y 8mo) to determine the prevalence of metabolic syndrome and CVD risk factors, and were compared to age-matched, population norms from the National Health and Nutrition Examination Survey (NHANES) registry. The Framingham Heart Study (FHS) CVD risk estimation was also used to evaluate an individual's risk for CVD.
resultsMetabolic syndrome was identified in 17.1% of the cohort, higher than the 10% in the NHANES registry. The FHS CVD 30-year lipid and body mass index (BMI)-based risk factor results showed that 20% to 40% of the cohort was at greater risk of developing CVD (BMI-based: 39.7% 'full' CVD risk factor; lipid-based: 26.5% 'full' CVD risk factor) as compared to the FHS normative population data. There was a positive correlation between GMFCS level, waist circumference (r=0.28, p=0.02), and waist-to-hip ratio (r=0.28, p=0.02).
interpretationAdults with CP are at higher risk of CVD and metabolic syndrome compared to the general population, which is probably because of impaired mobility.
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