ArticleInternational journal of ophthalmology2019
Genome-wide DNA hypermethylation and homocysteine increase a risk for myopia.
Article in International journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- DNA methylation biomarkers and myopia: a multi-omics study integrating GWAS, mQTL and eQTL data.Clinical epigenetics · 2024Pooled it
- From Genetic Diagnosis to Therapeutic Implementation in Retinal Diseases: Translational Advances and Persistent Bottlenecks.Biomedicines · 2026Review
- Research Progress of Epigenetic Modifications in Myopia.International journal of medical sciences · 2025Review
- Metabolomics analysis of aqueous humor from patients with high-myopia complicated nuclear cataract.Frontiers in medicine · 2025Article
- Review
- miR-328-3p Affects Axial Length Via Multiple Routes and Anti-miR-328-3p Possesses a Potential to Control Myopia Progression.Investigative ophthalmology & visual science · 2022Article
- Decreased Levels of DNA Methylation in the PCDHA Gene Cluster as a Risk Factor for Early-Onset High Myopia in Young Children.Investigative ophthalmology & visual science · 2022Article
- Sports and Myopia: An Investigation on the Prevalence and Risk Factors of Myopia in Young Sports-Related Groups in Tianjin, China.Investigative ophthalmology & visual science · 2022Article
- Identification of lncRNAs Associated with the Pathogenesis of Diabetic Retinopathy: From Sequencing Analysis to Validation viaComputational and mathematical methods in medicine · 2022Article
- Differential methylation of microRNA encoding genes may contribute to high myopia.Frontiers in genetics · 2022Article
- Functional integration of eye tissues and refractive eye development: Mechanisms and pathways.Experimental eye research · 2021Review
- Genome-wide analysis of retinal transcriptome reveals common genetic network underlying perception of contrast and optical defocus detection.BMC medical genomics · 2021Article
- IMI 2021 Yearly Digest.Investigative ophthalmology & visual science · 2021Review
- Hsa-miR-155 regulates the cell cycle and barrier function of corneal endothelial cells through E2F2.American journal of translational research · 2021Article
- Associations between near work, outdoor activity, parental myopia and myopia among school children in Aba, Nigeria.International journal of ophthalmology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo test for the association between genome-wide methylation and myopia in human and mice.
methods
resultsThe
conclusion
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.