Evidence map›Paper›PMID 30662811›Full record

ArticleAmerican journal of cancer research2018

Cellular 5-hydroxylmethylcytosine content determines tumorigenic potential and prognosis of pancreatic ductal adenocarcinoma.

Yi-Lng Chen, Chun-Mei Hu, Jeh-Ting Hsu, Chin-Chun Chang, Ting-Yu Huang, Pei-Hsun Chiang, Wei-Yi Chen, Yu-Ting Chang, Ming-Chu Chang, Yu-Wen Tien and 3 more

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Yi-Lng ChenGenomics Research Center, Academia Sinica Taipei, Taiwan.
Chun-Mei HuGenomics Research Center, Academia Sinica Taipei, Taiwan.
Jeh-Ting HsuDepartment of Information Management, Hsing Wu University New Taipei City, Taiwan.
Chin-Chun ChangGenomics Research Center, Academia Sinica Taipei, Taiwan.
Ting-Yu HuangGenomics Research Center, Academia Sinica Taipei, Taiwan.
Pei-Hsun ChiangGenomics Research Center, Academia Sinica Taipei, Taiwan.
Wei-Yi ChenInstitute of Biochemistry and Molecular Biology, National Yang Ming University Taipei, Taiwan.
Yu-Ting ChangDepartment of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University Taipei, Taiwan.
Ming-Chu ChangDepartment of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University Taipei, Taiwan.
Yu-Wen TienDepartment of Surgery, National Taiwan University Hospital, College of Medicine, National Taiwan University Taipei, Taiwan.
Eva Yhp LeeDepartment of Biological Chemistry, University of California Irvine, CA, USA.
Yung-Ming JengDepartment of Pathology, National Taiwan University Hospital, Graduate Institute of Pathology, College of Medicine, National Taiwan University Taipei, Taiwan.
Wen-Hwa LeeGenomics Research Center, Academia Sinica Taipei, Taiwan.
Genomics Research Center, Academia Sinica · TWUniversity of California, Irvine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We stratified pancreatic ductal adenocarcinoma (PDAC) based on the tumorigenic properties of cancer cells, and aimed to identify clinically useful immunohistochemical (IHC) markers with mechanistic insights. The tumorigenic properties of PDACs were determined using patient-derived xenograft in NOD/SCID/IL2Rγ

Indexed as

5hmClineage plasticitypancreatic cancerprognostic biomarkertumorigenicity

Identifiers

PMID30662811
PMCPMC6325483
OpenAlexW2991537290

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.