Evidence map›Paper›PMID 30662713›Full record

ArticleRoyal Society open science2018

A continuous model of physiological prion aggregation suggests a role for Orb2 in gating long-term synaptic information.

Michele Sanguanini, Antonino Cattaneo

Open access · goldAbstract read
In one paragraph

Article in Royal Society open science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Role of CPEBs in Learning and Memory.Journal of neurochemistry · 2025
    Review
  2. The elusive transcriptional memory trace.Oxford open neuroscience · 2022
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Michele SanguaniniScuola Normale Superiore, Piazza dei Cavalieri, 7, 56126 Pisa, Italy.ORCID 0000-0002-7142-3807
Antonino CattaneoScuola Normale Superiore, Piazza dei Cavalieri, 7, 56126 Pisa, Italy.
Google (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The regulation of mRNA translation at the level of the synapse is believed to be fundamental in memory and learning at the cellular level. The family of cytoplasmic polyadenylation element binding (CPEB) proteins emerged as an important RNA-binding protein family during development and in adult neurons.

Indexed as

amyloidlong-term memoryOrb2physiological prionsynaptic plasticity

Identifiers

PMID30662713
PMCPMC6304141
OpenAlexW2908977545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.