Hypermethylated

Haizhong Jiang, Linyin Sun, Chunyan Hu, Yaqing Wang

Open access · greenAbstract read

In one paragraph

Article in American journal of translational research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it

0cells of the map it votes in

4citing papers in PubMed

0.5field-weighted citation impact, top 35% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

Dual role of WNT10A in promoting the malignancy of glioblastoma and remodeling the tumor microenvironment.Neuro-oncology · 2025
Article
Prognostic role of Wnt and Fzd gene families in acute myeloid leukaemia.Journal of cellular and molecular medicine · 2021
Article
Emerging Roles of Wnt Ligands in Human Colorectal Cancer.Frontiers in oncology · 2020
Review
Using WGCNA (weighted gene co-expression network analysis) to identify the hub genes of skin hair follicle development in fetus stage of Inner Mongolia cashmere goat.PloS one · 2020
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Haizhong JiangDepartment of Gastroenterology, Ningbo First Hospital 59 Liuting Street, Ningbo 315010, People's Republic of China.

Linyin SunDepartment of Gastroenterology, Ningbo First Hospital 59 Liuting Street, Ningbo 315010, People's Republic of China.

Chunyan HuDepartment of Gastroenterology, Ningbo First Hospital 59 Liuting Street, Ningbo 315010, People's Republic of China.

Yaqing WangLaboratory of Molecular Medicine, Ningbo First Hospital 59 Liuting Street, Ningbo 315010, People's Republic of China.

Ningbo First Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is a heterogeneous disease in which unique subtypes are characterized by distinct genetic and epigenetic alterations. DNA methylation, a well-documented epigenetic modification, is a promising biomarker for the diagnosis and prognosis of cancers, including CRC.

Indexed as

CRCdiagnosisDNA methylationTCGAWNT10A

Identifiers

PMID30662671

PMCPMC6325495

OpenAlexW2991073170

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.