Evidence map›Paper›PMID 30662663›Full record

ArticleAmerican journal of translational research2018

Anti-CD200 attenuates concanavalin A induced hepatitis via modulating the imbalance of CD4

Xiaohong Zhao, Shuo Ding, Chuan Geng, Zhong Man, Mengzhi Pan, Leilei Sun, Baoji Hu, Hua Wang

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xiaohong ZhaoDepartment of Anesthesiology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center 2800 Gongwei Road, Huinan Town, Pudong, Shanghai 201399, China.
Shuo DingDepartment of Intensive Care, Fengxian People's Hospital 51 West Renmin Rd, Fenxian, Xuzhou 221700, China.
Chuan GengDepartment of Anesthesiology, Fengxian People's Hospital 51 West Renmin Rd, Fenxian, Xuzhou 221700, China.
Zhong ManDepartment of Anesthesiology, Fengxian People's Hospital 51 West Renmin Rd, Fenxian, Xuzhou 221700, China.
Mengzhi PanDepartment of Anesthesiology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center 2800 Gongwei Road, Huinan Town, Pudong, Shanghai 201399, China.
Leilei SunDepartment of Anesthesiology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center 2800 Gongwei Road, Huinan Town, Pudong, Shanghai 201399, China.
Baoji HuDepartment of Anesthesiology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center 2800 Gongwei Road, Huinan Town, Pudong, Shanghai 201399, China.
Hua WangDepartment of Anesthesiology, Affiliated Hospital of Guilin Medical University 15 Lequn Rd, Guilin 541001, China.
Fudan University · CNPudong Medical Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis occurs in critical ill patients with bad morbidity and mortality. It is known that imbalance of Th1 and Th2 lymphocytes differentiations plays a key role in its mechanisms. Recent studies indicated that type 1 membrane glycoprotein CD200 serves as co-inhibitory molecule, negatively regulating the immune response. In regard of this, we used Concanavalin A (Con A) induced liver injury model to research the effect of CD200 on the differentiation of CD4

Indexed as

CD200CD4+ T lymphocyte differentiationHepatitismice

Identifiers

PMID30662663
PMCPMC6325521
OpenAlexW3022593466

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.