Evidence map›Paper›PMID 30662590›Full record

ReviewAmerican journal of translational research2018

Organ transplantation and gut microbiota: current reviews and future challenges.

Jie Xiao, Zhao Peng, Yuxiao Liao, Hui Sun, Weiqiang Chen, Xing Chen, Zhanjie Wei, Chuanlei Yang, Andreas K Nüssler, Jinping Liu and 1 more

Open access · greenAbstract readReview
In one paragraph

Review in American journal of translational research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Kidney transplantation and gut microbiota.Clinical kidney journal · 2024
    Review
  2. Review
  3. Article
  4. Observational
  5. Review
  6. Review
  7. Review
  8. Review
  9. Microbiota, renal disease and renal transplantation.World journal of transplantation · 2021
    Review
  10. Review
  11. Article
  12. Gastrointestinal complications after kidney transplantation.World journal of gastroenterology · 2020
    Review
  13. Article
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jie XiaoDepartment of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430022, Hubei, China.
Zhao PengDepartment of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, Tongji Medical College, Huazhong University of Science and Technology 13 Hangkong Road, Wuhan 430030, China.
Yuxiao LiaoDepartment of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, Tongji Medical College, Huazhong University of Science and Technology 13 Hangkong Road, Wuhan 430030, China.
Hui SunDepartment of Cardio-Thoracic Surgery, Ganzhou People's Hospital Ganzhou 341000, Jiangxi, China.
Weiqiang ChenDepartment of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430022, Hubei, China.
Xing ChenDepartment of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430022, Hubei, China.
Zhanjie WeiDepartment of Thyroid Surgery, Central Hospital of Wuhan Wuhan 430022, Hubei, China.
Chuanlei YangDepartment of Cardiovascular Surgery, Central Hospital of Wuhan Wuhan 430022, Hubei, China.
Andreas K NüsslerDepartment of Traumatology, BG Trauma Center, University of Tübingen Schnarrenbergstr. 95, Tübingen 72076, Germany.
Jinping LiuDepartment of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430022, Hubei, China.
Wei YangDepartment of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, Tongji Medical College, Huazhong University of Science and Technology 13 Hangkong Road, Wuhan 430030, China.
Huazhong University of Science and Technology · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organ transplantation is often the only effective treatment for patients with end-stage diseases, such as heart, liver, kidney and small bowel failure and is carried out frequently worldwide. Still the post-transplantation complications remain health- and life-threatening outcome that needed to be resolved. With the rapid development of molecular technologies in recent years, more and more researchers realize that the gut microbiota may play a critical role in human diseases. The intestinal microbiome has been proved to provide a lot of functions to the host, such as digesting food, modulating metabolism, promoting angiogenesis and regulating the immune system. Several studies have investigated the alteration of intestinal microbiota in post-transplantation patients and observed significant changes in the intestinal microbiome compared to the pre-transplant condition. Due to the abovementioned features that the gut microbiota may be used in the prognosis of clinical outcome of organ transplantation. In addition, the FMT (fecal microbiota transplantation), probiotics and prebiotics as the newest therapy methods, effectiveness of which has been verified in some diseases, such as Clostridium difficile infection, inflammatory bowel disease and other chronic disorders, might be used as the prognosis tool in organ transplantation as well. The purpose of this present review is to elucidate the relationship between gut microbiota and organ transplantation as well as the potential use of new therapies like fecal microbiota transplantation, probiotic and prebiotic administration after the transplantation, and provide some ideas for future researches in field of organ transplantation.

Indexed as

complicationfecal microbiota transplantationgut microbiotaOrgan transplantationprebioticprobioticprognosis

Identifiers

PMID30662590
PMCPMC6291689
OpenAlexW2988089764

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.