ArticleInternational journal of endocrinology2018
Autoimmune Diseases in Patients with Cushing's Syndrome after Resolution of Hypercortisolism: Case Reports and Literature Review.
Article in International journal of endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 23 citations in OpenAlex.
- Increased cytokine production capacity and persistent inflammation after achieving remission of Cushing's syndrome.Journal of clinical & translational endocrinology · 2026Article
- A case of immune thrombocytopenia aggravated by therapy for hypercortisolism in adrenocortical carcinoma.Therapeutic advances in endocrinology and metabolism · 2026Article
- Management of Osilodrostat Therapy in Patients With Cushing's Syndrome: A Modified Delphi Consensus Panel.Journal of the Endocrine Society · 2025Article
- Sarcoidosis unmasked by Cushing's syndrome: successful surgical resolution.Archives of medical science : AMS · 2025Article
- Cushing's syndrome developing myasthenia gravis with takotsubo cardiomyopathy after adrenalectomy: a case report.BMC neurology · 2024Article
- Implications of Dysnatremia and Endocrine Disturbances in COVID-19 Patients.International journal of molecular sciences · 2024Review
- Emergence of De Novo Conditions Following Remission of Cushing Syndrome: A Case Report and Scoping Review.Endocrinology, diabetes & metabolism · 2024Article
- Unexpected exacerbation of cryptococcal meningitis after unilateral adrenalectomy in a PMAH patient: a case report and literature review.BMC endocrine disorders · 2023Review
- Major immunophenotypic abnormalities in patients with primary adrenal insufficiency of different etiology.Frontiers in immunology · 2023Article
- Glucocorticoid excess and COVID-19 disease.Reviews in endocrine & metabolic disorders · 2021Review
- Adrenal Cushing syndrome in a patient with corticosteroid-treated asthma and worsening diabetes mellitus.BMJ case reports · 2021Article
- Case of Cyclic Cushing's Disease with Improvement of Psoriatic Skin Lesions During a Period of Hypercortisolemia.Journal of the Endocrine Society · 2021Article
- Management of thyrotoxicosis occurring after surgery for Cushing's disease: a case series.Gland surgery · 2021Article
- Immune Reconstitution Inflammatory Syndrome Following Remission of Cushing's Syndrome and Review of Literature.Indian journal of endocrinology and metabolismReview
- THE OCCURRENCE OF SUBACUTE THYROIDITIS AFTER THE AMELIORATION OF HYPERCORTISOLISM FOLLOWING TRANSSPHENOIDAL SURGERY IN CUSHING'S DISEASE.Acta endocrinologica (Bucharest, Romania : 2005)Article
- A Case Report of Cushing's Disease Presenting With Psychosis and Muscle Weakness Postpartum.Journal of investigative medicine high impact case reportsArticle
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionCushing's syndrome (CS) is a clinical condition characterized by excessive cortisol production, associated with metabolic complications, such as diabetes mellitus, dyslipidemia, metabolic syndrome, hypertension, and cardiovascular diseases. Nowadays, the occurrence of autoimmune diseases in CS have not been completely evaluated in the previous studies.
objectiveThe aim of this study was to evaluate the occurrence of autoimmune diseases in CS patients after successfully treated. MATERIALS AND
methodsFrom January 2001 to December 2017, in our Secondary Hypertension Unit, we evaluated 147 CS patients (91 with ACTH-independent disease, 54 with ACTH-dependent disease, and 2 patients with ectopic ACTH production.
results109 CS patients (74.1%) were surgically treated (67 ACTH-independent CS patients (61.5%) undergone adrenalectomy and 42 ACTH-dependent CS (38.5%) undergone transsphenoidal surgery) and evaluated after 6, 12, and 24 months after clinical and biochemical remission of disease. In 9 (8.3%) of overall treated CS patients (8.3%), during follow-up, we observed the onset of some manifestations of autoimmune diseases. In particular, one patient had a systemic lupus erythematosus, one patient had rheumatoid arthritis, 4 patients reported autoimmune thyroiditis (Basedow-Graves' disease and Hashimoto's thyroiditis), one patient had clinical features of psoriasis, one patient showed myasthenia gravis, and one patient had giant cell arteritis.
conclusionsOur results demonstrate that patients successfully treated for CS could develop autoimmune diseases. Therefore, after treatment, CS patients need to be strictly monitored in order to evaluate the possible onset of autoimmune diseases.
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