Trial reportMediators of inflammation2018
Inflammatory Profiles in Depressed Adolescents Treated with Fluoxetine: An 8-Week Follow-up Open Study.
Trial report in Mediators of inflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Inflammation and depression in young people: a systematic review and proposed inflammatory pathways.Molecular psychiatry · 2022Pooled it
- The relationship between serum resolvin D1, NLRP3, cytokine levels, and adolescents with first-episode medication-naïve major depressive disorder.BMC psychiatry · 2024Trial
- Combining neurobiological markers and a sociodemographic risk score to predict adolescent depression - An IDEA RiSCo prospective cohort study.Molecular psychiatry · 2026Article
- Neuroimmune Dysregulation and the Role of IL-10 in Depression: A Systematic Review.Brain sciences · 2026Review
- Integrative In Silico Analysis of miRNA-mRNA Regulatory Networks in the Prefrontal Cortex of Individuals with Psychiatric Disorders Who Died by Suicide.International journal of molecular sciences · 2026Article
- Microglial Activation in Cerebrovascular Accidents and the Manifestation of Major Depressive Disorder: A Comprehensive Review.Brain sciences · 2025Review
- SSRI-induced modulation of cytokines, barrier permeability, and BDNF in adolescent depression.BMC psychiatry · 2025Article
- Dysregulated miR-1246 and miR-1253 link inflammatory protein markers in plasma to major depressive disorder in female adolescents.Brain, behavior, & immunity - health · 2025Article
- Suicide attempt predictors among adolescents exhibiting non-suicidal self-injury: A six-week follow-up open study.World journal of psychiatry · 2025Article
- CD4 + T lymphocyte and cytokine profiles in depressive disorders.BMC psychiatry · 2025Article
- Unveiling the Anti-Inflammatory Effects of Antidepressants: A Systematic Review of Human Studies over the Last Decade.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Tofacitinib prevents depressive-like behaviors through decreased hippocampal microgliosis and increased BDNF levels in both LPS-induced and CSDS-induced mice.Acta pharmacologica Sinica · 2025Article
- Investigating the relationship between inflammatory cytokines and adolescent depression: a comparative analysis.Frontiers in psychiatry · 2025Article
- The impact of BDNF and CD4 + T cell crosstalk on depression.Immunologic research · 2024Article
- Inflammation and immune system pathways as biological signatures of adolescent depression-the IDEA-RiSCo study.Translational psychiatry · 2024Article
- Impacts of inflammatory cytokines on depression: a cohort study.BMC psychiatry · 2024Article
- Review
- Biomarkers associated with treatment outcome in young people with depression: A systematic review.Neuroscience applied · 2024Review
- Is the acquired hypothyroidism a risk factor for developing psychiatric disorders?Frontiers in psychiatry · 2024Review
- Upregulation of S100A8 in peripheral blood mononuclear cells from patients with depression treated with SSRIs: a pilot study.Proteome science · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Changes in cytokine levels in major depression and during treatment have been reported in adults. However, few studies have examined cytokine levels in an adolescent sample despite this being a common age of onset.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.