Evidence map›Paper›PMID 30662341›Full record

ArticleInternational journal of medical sciences2019

Nonselective Cyclooxygenase Inhibition Retards Cyst Progression in a Murine Model of Autosomal Dominant Polycystic Kidney Disease.

Min Zhang, Manakan B Srichai, Min Zhao, Jian Chen, Linda S Davis, Guanqing Wu, Matthew D Breyer, Chuan-Ming Hao

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Collecting Duct-Targeted Lipid Nanoparticles DeliverbioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Min ZhangDivision of Nephrology, Huashan Hospital, Fudan University, Shanghai, China.
Manakan B SrichaiDepartment of Medicine, Division of Nephrology, Vanderbilt University, Nashville, TN.
Min ZhaoDepartment of Medicine, Division of Nephrology, Vanderbilt University, Nashville, TN.
Jian ChenDepartment of Medicine, Division of Nephrology, Vanderbilt University, Nashville, TN.
Linda S DavisDepartment of Medicine, Division of Nephrology, Vanderbilt University, Nashville, TN.
Guanqing WuDepartment of Medicine, Division of Nephrology, Vanderbilt University, Nashville, TN.
Matthew D BreyerBiotechnology Discovery Research, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46225, USA.
Chuan-Ming HaoDivision of Nephrology, Huashan Hospital, Fudan University, Shanghai, China.
Vanderbilt University · USNashville VA Medical Center · USEli Lilly (United States) · USHuashan Hospital · CN

Funding

Renal Medullary COX2 in Blood Pressure RegulationR01DK071876 · NIDDK · VANDERBILT UNIVERSITY · PI HAO, CHUAN-MING · 2005 to 2009
$1.4M
Role of Cyclooxygenase Stimulated Neovascularization in Diabetic NephropathyR01DK074116 · NIDDK · VANDERBILT UNIVERSITY · PI HAO, CHUAN-MING · 2005 to 2008
$1.1M
NIDDK NIH HHS R01 DK071876NIDDK NIH HHS R01 DK074116
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell ProliferationCyclooxygenase InhibitorsCystsDinoprostoneDisease Models, AnimalDisease ProgressionGlomerular Filtration RateHumansMiceMolecular Targeted TherapyMutationPolycystic Kidney, Autosomal DominantProstaglandin-Endoperoxide SynthasesProstaglandin-E SynthasesProstaglandinsCyclooxygenase InhibitorsDinoprostoneProstaglandin-Endoperoxide SynthasesProstaglandin-E SynthasesProstaglandinsSulindacTRPP Cation ChannelsADPKDCOX2PKD2prostanoidSulindac

Identifiers

PMID30662341
PMCPMC6332488
OpenAlexW2909120543

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.