Evidence map›Paper›PMID 30662338›Full record

ArticleInternational journal of medical sciences2019

Activation of the Nrf2/HO-1 signaling pathway contributes to the protective effects of baicalein against oxidative stress-induced DNA damage and apoptosis in HEI193 Schwann cells.

Jae Yeob Jeong, Hee-Jae Cha, Eun Ok Choi, Cheol Hong Kim, Gi-Young Kim, Young Hyun Yoo, Hye-Jin Hwang, Hwan Tae Park, Hyun Min Yoon, Yung Hyun Choi

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 74 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Hydroethanolic Extract ofPlants (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Baicalein Induces GMolecules (Basel, Switzerland) · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jae Yeob JeongDepartment of Acupuncture and Moxibution, Dongeui University College of Korean Medicine, Busan 47227, Republic of Korea.
Hee-Jae ChaDepartment of Parasitology and Genetics, Kosin University College of Medicine, Busan 49267, Republic of Korea.
Eun Ok ChoiAnti-Aging Research Center and Department of Biochemistry, Dongeui University College of Korean Medicine, Busan 47227, Republic of Korea.
Cheol Hong KimDepartment of Acupuncture and Moxibution, Dongeui University College of Korean Medicine, Busan 47227, Republic of Korea.
Gi-Young KimDepartment of Marine Life Sciences, Jeju National University, Jeju 63243, Republic of Korea.
Young Hyun YooDepartment of Anatomy and Cell Biology, Mitochondria Hub Regulation Center, College of Medicine, Dong-A University, Busan 49201, Republic of Korea.
Hye-Jin HwangDepartment of Food and Nutrition, College of Nursing, Healthcare Sciences & Human Ecology, Dongeui University, Busan 47340, Republic of Korea.
Hwan Tae ParkDepartment of Physiology, Peripheral Neuropathy Research Center, College of Medicine, Dong-A University, Busan 49201, Republic of Korea.
Hyun Min YoonDepartment of Acupuncture and Moxibution, Dongeui University College of Korean Medicine, Busan 47227, Republic of Korea.
Yung Hyun ChoiAnti-Aging Research Center and Department of Biochemistry, Dongeui University College of Korean Medicine, Busan 47227, Republic of Korea.
Dong-Eui University · KRDong-A University · KRJeju National University · KRKosin University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Baicalein, a flavonoid extracted from the roots of

Indexed as

AntioxidantsApoptosisCell Line, TumorCell SurvivalDNA DamageFlavanonesHeme Oxygenase-1HumansHydrogen PeroxideMembrane Potential, MitochondrialNF-E2-Related Factor 2OxidantsOxidative StressPhosphorylationReactive Oxygen SpeciesSchwann CellsAntioxidantsbaicaleinFlavanonesHeme Oxygenase-1HMOX1 protein, humanHydrogen PeroxideNFE2L2 protein, humanNF-E2-Related Factor 2OxidantsReactive Oxygen SpeciesapoptosisBaicaleinDNA damageNrf2/HO-1oxidative stressSchwann cells

Identifiers

PMID30662338
PMCPMC6332480
OpenAlexW2910723078

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.