Evidence map›Paper›PMID 30662125›Full record

ArticleAnesthesia, essays and researches

Comparison of Nebulized Ketamine with Nebulized Magnesium Sulfate on the Incidence of Postoperative Sore Throat.

Sivakumar Segaran, Arish T Bacthavasalame, Ranjan R Venkatesh, Mamie Zachariah, Sagiev Koshy George, Ravichandran Kandasamy

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Anesthesia, essays and researches. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06168981 (The Effect of Preoperative Chewing Gum on Anxiety and Sore Throat in Patients With Laryngeal Mask Airway), which is not on this map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06168981 naunknown statusnot on this map

The Effect of Preoperative Chewing Gum on Anxiety and Sore Throat in Patients With Laryngeal Mask Airway: A Randomised Controlled Trial

TypeinterventionalSponsorAnkara Medipol UniversityRan2023 to 2024Enrolled92ConditionsLaryngeal Mask, Throat Pain, AnxietyArmsChewing Gum
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  7. Traditional Chinese Medicine Compounds ContainingEvidence-based complementary and alternative medicine : eCAM · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sivakumar SegaranDepartment of Anaesthesiology and Critical Care, Pondicherry Institute of Medical Sciences, Puducherry, India.
Arish T BacthavasalameDepartment of Anaesthesiology and Critical Care, Pondicherry Institute of Medical Sciences, Puducherry, India.
Ranjan R VenkateshDepartment of Anaesthesiology and Critical Care, Pondicherry Institute of Medical Sciences, Puducherry, India.
Mamie ZachariahDepartment of Anaesthesiology and Critical Care, Pondicherry Institute of Medical Sciences, Puducherry, India.
Sagiev Koshy GeorgeDepartment of Anaesthesiology and Critical Care, Pondicherry Institute of Medical Sciences, Puducherry, India.
Ravichandran KandasamyDepartment of Anaesthesiology and Critical Care, Pondicherry Institute of Medical Sciences, Puducherry, India.
Pondicherry Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative sore throat (POST) is a known complication following general anesthesia requiring endotracheal intubation. Its incidence ranges from 21% to 65% and remains the eighth most undesirable postoperative event. Various measures have been tried to decrease the incidence of sore throat with various success rates.

aimThis study aimed at reducing the incidence of POST with ketamine and magnesium sulfate nebulization. SETTINGS AND

designThis study is a prospective randomized, double-blinded study. MATERIALS AND

methodsAfter Institutional Ethics Committee approval and written informed consent, 80 patients who fulfilled the inclusion and exclusion criteria were randomly divided into two groups to receive magnesium sulfate 250 mg in 5 ml saline in Group A and ketamine 50 mg in 5 ml saline nebulization in Group B before the start of general anesthesia. All patients received standard anesthesia protocol. After extubation, all patients were enquired about the incidence and severity of sore throat at 0, 2, 4, 6, and 24 h. STATISTICAL ANALYSIS USED: Paired

resultsThere were no differences in the demographic profile, duration of laryngoscopy, time taken to intubate, and duration of surgery between the two groups. The incidence and severity of sore throat were significantly decreased in ketamine group at 4 and 6 h when compared to magnesium sulfate group.

conclusionNebulization with ketamine 50 mg significantly decreases the incidence of POST when compared to magnesium sulfate 250 mg.

Indexed as

Endotracheal intubationgeneral anesthesiaketaminemagnesium sulfatenebulizationpostoperative sore throat

Identifiers

PMID30662125
PMCPMC6319074
OpenAlexW2950275638

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.